Issues and Prospects of Current Endoscopic Treatment Strategy for Superficial Non-Ampullary Duodenal Epithelial Tumors

• Published in: Current oncology (Toronto) Vol. 29; no. 10; pp. 6816 - 6825
• Main Authors: Suwa, Tetsuya, Yoshida, Masao, Ono, Hiroyuki
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 22.09.2022; MDPI
• Subjects: Adenoma - pathology; Adenoma - surgery; Care and treatment; cold snare polypectomy; Colonic Polyps - pathology; Colonoscopy; conventional endoscopic mucosal resection; Diagnosis; Duodenal Neoplasms - pathology; Duodenal Neoplasms - surgery; Duodenum - pathology; Duodenum - surgery; endoscopic full-thickness resection; endoscopic submucosal dissection; Endoscopy; Gastrointestinal diseases; Humans; Opinion; superficial non-ampullary duodenal epithelial tumor; Treatment Outcome; Tumors; underwater endoscopic mucosal resection; Japan; superficial non-ampullary duodenal epithelial tumor; cold snare polypectomy; conventional endoscopic mucosal resection; treatment strategy; laparoscopic and endoscopic cooperative surgery for duodenal tumors; endoscopic submucosal dissection; underwater endoscopic mucosal resection; endoscopic full-thickness resection
• ISSN: 1718-7729; 1198-0052; 1718-7729
• DOI: 10.3390/curroncol29100537

An increasing number of duodenal tumors are being diagnosed over the years, leading to increased confusion regarding the choice of treatment options. Small-to-large tumors and histological types vary from adenoma to carcinoma, and treatment methods may need to be selected according to lesion characteristics. Because of its anatomic characteristics, complications are more likely to occur in the duodenum than in other gastrointestinal organs. Several reports have described the outcomes of conventional endoscopic mucosal resection, endoscopic submucosal dissection, cold snare polypectomy, underwater endoscopic mucosal resection, endoscopic full-thickness resection, and laparoscopic and endoscopic cooperative surgery for duodenal tumors. However, even in the guidelines set out by various countries, only the treatment methods are listed, and no clear treatment strategies are provided. Although there are few reports with a sufficiently high level of evidence, considering the currently available treatment options is essential. In this report, we reviewed previous reports on each treatment strategy, discussed the current issues and prospects, and proposed the best possible treatment strategy.