The Role of Graphene Oxide Nanocarriers in Treating Gliomas

Gliomas are the most common primary malignant tumors of the central nervous system, and their conventional treatment involves maximal safe surgical resection combined with radiotherapy and temozolomide chemotherapy; however, this treatment does not meet the requirements of patients in terms of survi...

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Published inFrontiers in oncology Vol. 12; p. 736177
Main Authors Wang, Bin, Guo, Hanfei, Xu, Haiyang, Chen, Yong, Zhao, Gang, Yu, Hongquan
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 28.01.2022
Subjects
antitumor
cell cycle
graphene oxide
immunotherapy
invasion
metabolism
Oncology
graphene oxide
invasion
antitumor
cell cycle
immunotherapy
migration
metabolism
phototherapy
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Summary:Gliomas are the most common primary malignant tumors of the central nervous system, and their conventional treatment involves maximal safe surgical resection combined with radiotherapy and temozolomide chemotherapy; however, this treatment does not meet the requirements of patients in terms of survival and quality of life. Graphene oxide (GO) has excellent physical and chemical properties and plays an important role in the treatment of gliomas mainly through four applications, viz. direct killing, drug delivery, immunotherapy, and phototherapy. This article reviews research on GO nanocarriers in the treatment of gliomas in recent years and also highlights new ideas for the treatment of these tumors.
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This article was submitted to Pharmacology of Anti-Cancer Drugs, a section of the journal Frontiers in Oncology
Reviewed by: Naresh Kumar Rajendran, University of Rochester, United States; Mariana Tasso, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina
Edited by: Jinming Zhang, Chengdu University of Traditional Chinese Medicine, China
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2022.736177