Suppression of the DTH reaction in mice by means of moxibustion at electro-permeable points

The effects of moxibustion stimulation on picryl chloride-induced cutaneous contact hypersensitivity, a delayed type of hypersensitivity (DTH) reaction, were investigated in mice. Three electro-permeable points (B-20, LI-15, S-36) were selected as moxibustion points. Moxibustion at point B-20 (splee...

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Published inThe American journal of Chinese medicine (1979) Vol. 17; no. 3-4; p. 139
Main Authors Tohya, K, Mastrogiovanni, F, Sugata, R, Ohnishi, M, Kuroiwa, K, Toda, S, Kimura, M, Kawamata, J
Format Journal Article
LanguageEnglish
Published Singapore 1989
Subjects
Acupuncture Points
Animals
Dermatitis, Contact - pathology
Dermatitis, Contact - prevention & control
Ear - pathology
Female
Immunity, Cellular
Immunization, Passive
Mice
Mice, Inbred BALB C
Moxibustion
Picryl Chloride
T-Lymphocytes - immunology
T-Lymphocytes - transplantation
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Summary:The effects of moxibustion stimulation on picryl chloride-induced cutaneous contact hypersensitivity, a delayed type of hypersensitivity (DTH) reaction, were investigated in mice. Three electro-permeable points (B-20, LI-15, S-36) were selected as moxibustion points. Moxibustion at point B-20 (spleen associated point) significantly suppressed the DTH reaction. Adoptive transfer of spleen T cells from moxibustion-stimulated donors resulted in an increased suppression of the DTH reaction in the recipients. These studies suggest that suppression of the DTH reaction with moxibustion may be related to cellular immunity, especially to the induction of the suppressive activity of T cells in the spleen.
ISSN:0192-415X
DOI:10.1142/s0192415x8900022x