When to manage level V in head and neck carcinoma?

• Published in: The Laryngoscope Vol. 121; no. 3; p. 545
• Main Authors: Naiboğlu, Bariş, Karapinar, Uğur, Agrawal, Amit, Schuller, David E, Ozer, Enver
• Format: Journal Article
• Language: English
• Published: United States 01.03.2011
• Subjects: Accessory Nerve - surgery; Arteries - surgery; Clavicle - surgery; Humans; Hypopharyngeal Neoplasms - pathology; Hypopharyngeal Neoplasms - surgery; Laryngeal Neoplasms - pathology; Laryngeal Neoplasms - surgery; Lymph Nodes - pathology; Lymphatic Metastasis - pathology; Mouth Neoplasms - pathology; Mouth Neoplasms - surgery; Neck - blood supply; Neck Dissection - methods; Neck Muscles - pathology; Neck Muscles - surgery; Neoplasm Staging; Neoplasms, Unknown Primary - pathology; Neoplasms, Unknown Primary - surgery; Oropharyngeal Neoplasms - pathology; Oropharyngeal Neoplasms - surgery; Otorhinolaryngologic Neoplasms - pathology; Otorhinolaryngologic Neoplasms - secondary; Otorhinolaryngologic Neoplasms - surgery; Retrospective Studies
• ISSN: 1531-4995
• DOI: 10.1002/lary.21468

As superselective neck dissection strategy is gaining popularity to minimize postoperative morbidity and better life quality, we investigated the metastatic nodal status of level V neck lymph node group for head and neck squamous cell carcinoma in various primary sites. We have also aimed to display the impact of involvement of other nodal groups on level V. Retrospective review of histopathologic examination of case series at a comprehensive cancer center. The study group was composed of 107 patients who underwent a type of neck dissection including level V among 243 patients. The impact of primary site and metastatic nodal status of other levels on metastasis to level V involvement were evaluated. The most common primary tumor site was oropharynx (n = 43), followed by oral cavity (n = 32), larynx (n = 16), carcinoma of unknown primary (n = 10), and hypopharynx (n = 6). General pathologic N positivity for all levels was 78.3% (76 of 97) when 10 carcinoma of unknown primary patients were excluded. Level V was involved in 13 of 107 (12.1%) patients. Level V was not involved in any patient when the other levels were not involved (0 of 21). Even when considering only N+ patients, the ratio of N positivity for level V is still <20% (13 of 86, 15.1%). Because level V was not involved in any patient when the other levels were not involved, it might be reasonable to preserve level V especially in clinically and intraoperatively N0 patients.