Protein-protein docking benchmark 2.0: An update
We present a new version of the Protein–Protein Docking Benchmark, reconstructed from the bottom up to include more complexes, particularly focusing on more unbound–unbound test cases. SCOP (Structural Classification of Proteins) was used to assess redundancy between the complexes in this version. T...
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Published in | Proteins, structure, function, and bioinformatics Vol. 60; no. 2; pp. 214 - 216 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Hoboken
Wiley Subscription Services, Inc., A Wiley Company
01.08.2005
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Subjects | |
Online Access | Get full text |
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Summary: | We present a new version of the Protein–Protein Docking Benchmark, reconstructed from the bottom up to include more complexes, particularly focusing on more unbound–unbound test cases. SCOP (Structural Classification of Proteins) was used to assess redundancy between the complexes in this version. The new benchmark consists of 72 unbound–unbound cases, with 52 rigid‐body cases, 13 medium‐difficulty cases, and 7 high‐difficulty cases with substantial conformational change. In addition, we retained 12 antibody–antigen test cases with the antibody structure in the bound form. The new benchmark provides a platform for evaluating the progress of docking methods on a wide variety of targets. The new version of the benchmark is available to the public at http://zlab.bu.edu/benchmark2. Proteins 2005;60:214–216. © 2005 Wiley‐Liss, Inc. |
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Bibliography: | istex:F0C73345B4D0C22DA474688B158F2AE1A1A5FCC2 ark:/67375/WNG-RCRWBK75-R U.S. Department of Energy Computational Science Graduate Fellowship ArticleID:PROT20560 National Science Foundation - No. DBI-0078194; No. DBI-0133834; No. DBI-0116574 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0887-3585 1097-0134 |
DOI: | 10.1002/prot.20560 |