Effects of blood hematocrit on performance of endovascular coiling for treatment of middle cerebral artery (MCA) aneurysms: Computational study

• Published in: Interdisciplinary neurosurgery : Advanced techniques and case management Vol. 32; p. 101729
• Main Authors: Hariri, Saman, Mirzaei Poueinak, Milad, Hassanvand, Amin, Barzegar Gerdroodbary, M., Faraji, M.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.06.2023; Elsevier
• Subjects: Cerebral aneurysms; CFD; Coiling embolization; Hemodynamics; MCA; Porous media; CFD; Porous media; Cerebral aneurysms; MCA; Hemodynamics; Coiling embolization
• ISSN: 2214-7519; 2214-7519
• DOI: 10.1016/j.inat.2023.101729

Aneurysms with saccular cervical aneurysms are often treated with coiling embolism to prevent rupture and hemorrhage. This study attempted to examine the effects of coiling embolism on blood hemodynamics and bleeding from Middle cerebral artery (MCA) aneurysms. The pulsatile blood stream inside the heart is modeled using computational fluid dynamics by solving Reynolds Average Navier-stocks (RANS) equations. In this study, pressure, oscillatory shear index (OSI), and wall shear stress (WSS) on the sac wall are compared to reveal the high-risk zone at different times during the blood cycle. We also examine the role of coiling porosity in three different conditions of peak systolic blood hematocrit. The WSS value reaches its maximum near the neck of the sac, while the OSI value reaches its maximum near the dome of the aneurysm. Coiling also reduces OSI while having a limited impact on WSS near the neck, according to our results.