Muscle glycogen storage after different amounts of carbohydrate ingestion

• Published in: Journal of applied physiology (1985) Vol. 65; no. 5; p. 2018
• Main Authors: Ivy, J L, Lee, M C, Brozinick, Jr, J T, Reed, M J
• Format: Journal Article
• Language: English
• Published: United States 01.11.1988
• Subjects: Blood Glucose - metabolism; Dietary Carbohydrates - administration & dosage; Dietary Carbohydrates - metabolism; Glycogen - metabolism; Glycogen Synthase - metabolism; Humans; Insulin - blood; Lactates - blood; Lactic Acid; Male; Muscles - metabolism; Physical Exertion; Pulmonary Gas Exchange
• ISSN: 8750-7587
• DOI: 10.1152/jappl.1988.65.5.2018

The purpose of this study was to determine whether the rate of muscle glycogen storage could be enhanced during the initial 4-h period postexercise by substantially increasing the amount of the carbohydrate consumed. Eight subjects cycled for 2 h on three separate occasions to deplete their muscle glycogen stores. Immediately and 2 h after exercise they consumed either 0 (P), 1.5 (L), or 3.0 g glucose/kg body wt (H) from a 50% glucose polymer solution. Blood samples were drawn from an antecubital vein before exercise, during exercise, and throughout recovery. Muscle biopsies were taken from the vastus lateralis immediately, 2 h, and 4 h after exercise. Blood glucose and insulin declined significantly during exercise in each of the three treatments. They remained below the preexercise concentrations during recovery in the P treatment but increased significantly above the preexercise concentrations during the L and H treatments. By the end of the 4 h-recovery period, blood glucose and insulin were still significantly above the preexercise concentrations in both treatments. Muscle glycogen storage was significantly increased above the basal rate (P, 0.5 mumol.g wet wt-1.h-1) after ingestion of either glucose polymer supplement. The rates of muscle glycogen storage, however, were not different between the L and H treatments during the first 2 h (L, 5.2 +/- 0.9 vs. H, 5.8 +/- 0.7 mumol.g wet wt-1.h-1) or the second 2 h of recovery (L, 4.0 +/- 0.9 vs. H, 4.5 +/- 0.6 mumol.g wet wt-1. h-1).