Long-term effects of maternal prevention on children's dental decay and need for restorative treatment

• Published in: Community dentistry and oral epidemiology Vol. 41; no. 6; pp. 534 - 540
• Main Authors: Laitala, Marja L., Alanen, Pentti, Isokangas, Pauli, Söderling, Eva, Pienihäkkinen, Kaisu
• Format: Journal Article
• Language: English
• Published: Denmark Blackwell Publishing Ltd 01.12.2013
• Subjects: Child; Child, Preschool; Dental care; Dental caries; Dental Caries - epidemiology; Dental Caries - prevention & control; Dental Restoration, Permanent - statistics & numerical data; Dentistry; Disease transmission; Female; Finland - epidemiology; Follow-Up Studies; Humans; longitudinal study; Male; Maternal & child health; Mothers; mutans streptococci; Preventive Dentistry - methods; primary teeth; public dental health; Registries; Retrospective Studies; Risk Factors; Streptococcus mutans; Sweetening Agents - therapeutic use; xylitol; Xylitol - therapeutic use; Finland; dental caries; longitudinal study; xylitol; public dental health; mutans streptococci; primary teeth
• ISSN: 0301-5661; 1600-0528
• DOI: 10.1111/cdoe.12057

Objectives In a Finnish study carried out in 1990s, high‐caries‐risk mothers used xylitol gum on daily basis when their child was 3–24‐month old, whereas the high‐risk control mothers received biannual fluoride or chlorhexidine treatments. The maternal prevention reduced colonization of mutans streptococci and early childhood caries in children. The present retrospective study aimed to extend the post‐trial follow‐up to 10‐year‐old children (n = 148). Additionally, the dental health of these high‐caries‐risk children was compared with a reference group comprising the rest of the children in the same age cohort (n = 359). Methods The annual data on dental health and treatments were gathered from public dental care registers. Results The median caries‐free age (dmft = 0 and DMFT = 0) was 8.2 in the xylitol, 5.8 in the control, and 8.1 in the reference group (xylitol versus control, P = 0.005, HR = 1.75; 95% CI 1.18–2.60, reference versus xylitol, P = 0.410, HR = 1.13; 95% CI 0.84–1.51 Cox regression). Thus, the children in the xylitol group had caries‐free teeth longer than the control group. Compared to the reference group, the xylitol group did not show notable difference. Up to 4 years of age, figures for cumulative restorative treatment visits were 0.2 in the xylitol, 0.7 in the control, and 0.4 in the reference group (xylitol versus control P = 0.006, Student's t‐test). Conclusions The reduced mother–child transmission of mutans streptococci seems to have long‐term effects on children's dental health. The maternal use of xylitol reduces caries occurrence and need for restorative treatment in assumed high‐caries‐risk children to the average level of the whole age cohort.