Idiopathic bilateral vocal cord paralysis in infants: Case series and literature review

• Published in: The Laryngoscope Vol. 125; no. 7; p. 1724
• Main Authors: Lesnik, Maria, Thierry, Briac, Blanchard, Marion, Glynn, Fergal, Denoyelle, Françoise, Couloigner, Vincent, Garabedian, Noël, Leboulanger, Nicolas
• Format: Journal Article
• Language: English
• Published: United States 01.07.2015
• Subjects: Disease Management; Humans; Infant; Vocal Cord Paralysis - congenital; Vocal Cord Paralysis - therapy; tracheotomy; congenital; idiopathic; Bilateral vocal fold paralysis; noninvasive positive pressure ventilation
• ISSN: 1531-4995
• DOI: 10.1002/lary.25076

Vocal fold paralysis is the second most common congenital laryngeal anomaly in newborns. Bilateral paralysis is a severe condition and often remains of unknown etiology. We report our experience of congenital idiopathic bilateral vocal fold paralysis in newborns and infants, and discuss the therapeutic options. Retrospective review. A retrospective review was carried out at a single tertiary referral center over a 15-year period of children presenting with congenital idiopathic bilateral laryngeal paralysis (CIBP). Twenty-six patients were identified and managed over period of the study (mean follow-up, 6.7 years). A tracheostomy was eventually performed in 14 patients, 12 during the neonatal period. Endoscopic treatment was performed in 16 patients and an external approach in five patients after endoscopic failure. Three patients were managed by watchful waiting. Spontaneous recovery occurred in 16 patients (median age, 14.5 months), including nine with a tracheostomy. Decannulation was achieved in 12 patients (median age, 42 months), and noninvasive positive pressure ventilation (NPPV) was applied in six patients. Only inhomogeneous series of pediatric bilateral laryngeal palsies have been published so far, making it difficult to identify prognostic and predictive markers, as well as therapeutic guidelines. Focusing on CIBP, our data suggest that the management strategy must take into account the possibility of a delayed spontaneous recovery. NPPV is an interesting therapeutic tool in this situation. A systematic somatic assessment is mandatory to look for associated conditions.