Inclusion of pethidine in lidocaine for infiltration improves analgesia following tonsillectomy in children

• Published in: Acta anaesthesiologica Scandinavica Vol. 41; no. 2; pp. 214 - 217
• Main Authors: ELHAKIM, M., SALAM, A. Y. ABDUL, EID, A., KASCHEF, N., MOSTAFA, B. E.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.02.1997; Blackwell
• Subjects: Analgesics; Analgesics, Opioid - administration & dosage; Analgesics, Opioid - adverse effects; Anesthesia, Local; anesthetics; Anesthetics, Local - administration & dosage; Anesthetics, Local - adverse effects; Biological and medical sciences; Child; Child, Preschool; children; Double-Blind Method; Humans; Lidocaine - administration & dosage; Lidocaine - adverse effects; local: lidocaine; Medical sciences; Meperidine - administration & dosage; Meperidine - adverse effects; Neuropharmacology; opioid; opioid: pethidine; Pain Measurement; Pain, Postoperative - drug therapy; Pain, Postoperative - prevention & control; pain: postoperative; pediatric; peripheral; Pharmacology. Drug treatments; Premedication; receptor; surgery; Tonsillectomy; Human; Postoperative; Pethidine; Opiates; Narcotic analgesic; Local anesthetic; Analgesia; Regional anesthesia; Pain; Tonsillectomy; Surgery; ENT disease; Infiltration; Lidocaine; Child

Background:Previous work has demonstrated that pethidine exerts local anaesthetic effects on peripheral nerves in vivo. We examined the effects of infiltration anaesthesia by a combination of pethidine and lidocaine on post‐tonsillectomy pain and restlessness in children. Methods:Eighty children wer...