Inclusion of pethidine in lidocaine for infiltration improves analgesia following tonsillectomy in children
Background:Previous work has demonstrated that pethidine exerts local anaesthetic effects on peripheral nerves in vivo. We examined the effects of infiltration anaesthesia by a combination of pethidine and lidocaine on post‐tonsillectomy pain and restlessness in children. Methods:Eighty children wer...
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Published in | Acta anaesthesiologica Scandinavica Vol. 41; no. 2; pp. 214 - 217 |
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Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Publishing Ltd
01.02.1997
Blackwell |
Subjects | |
Online Access | Get full text |
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Summary: | Background:Previous work has demonstrated that pethidine exerts local anaesthetic effects on peripheral nerves in vivo. We examined the effects of infiltration anaesthesia by a combination of pethidine and lidocaine on post‐tonsillectomy pain and restlessness in children.
Methods:Eighty children were randomly allocated to receive peritonsillar infiltration postoperatively with 3 ml of lidocaine 2% (1.5 ml on each side) combined with either 0.1 ml pethidine, 10 mg · ml‐1, (pethidine group) or 0.1 ml normal saline (control group). Pain and behaviour were assessed at 1, 3, 6 and 12 h postoperatively and on the following morning by the patients and by a nurse blinded to previous treatment.
Results: Patients in the pethidine group had lower pain scores than those in the control group at rest as well as swallowing during the whole observation period (P < 0.05). Paracetamol was given to 34/40 children in the control group and to 6/40 children in the pethidine group. The corresponding figures for pethidine administration were 6/40 and 0/40, respectively. Patients in the pethidine group displayed a more rapid return to calm wakefulness than those in the control group (P <0.01).
Conclusions: Inclusion of a low dose of pethidine in lidocaine for tonsillar infiltration improves pain relief after tonsillectomy in children. |
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Bibliography: | istex:F04ECF6B297F8A5A9AB363E6370F9641DF3200E4 ArticleID:AAS214 ark:/67375/WNG-TM7P8BDT-S |
ISSN: | 0001-5172 1399-6576 |
DOI: | 10.1111/j.1399-6576.1997.tb04668.x |