Cardiovascular Risk in Psoriatic Patients Detected by Heart Rate Variability (HRV) Analysis

• Published in: Drug development research Vol. 75; no. S1; pp. S81 - S84
• Main Authors: Proietti, Ilaria, Raimondi, Gianfranco, Skroza, Nevena, Pampena, Riccardo, Bernardini, Nicoletta, La Viola, Giorgio, Nicolucci, Francesca, Tolino, Ersilia, Zuber, Sara, Scordamaglia, Beatrice, Balduzzi, Veronica, Soccodato, Valentina, Potenza, Concetta
• Format: Journal Article
• Language: English
• Published: United States Blackwell Publishing Ltd 01.11.2014; Wiley Subscription Services, Inc
• Subjects: Adult; autonomic nervous system; Blood pressure; Cardiac arrhythmia; Cardiovascular Diseases - epidemiology; cardiovascular risk; Case-Control Studies; Female; Heart rate; heart rate variability; Humans; Italy - epidemiology; Male; Psoriasis; Psoriasis - epidemiology; Risk Factors; Italy; autonomic nervous system; cardiovascular risk; heart rate variability; psoriasis
• ISSN: 0272-4391; 1098-2299
• DOI: 10.1002/ddr.21204

Postmarketing Phase IV Patients affected by severe psoriasis have an increased prevalence of cardiovascular () diseases as documented by several studies. Heart rate variability (HRV) is a noninvasive method to evaluate the autonomic control of the sinus node. In this study, HRV analysis has been used to evaluate whether young patients with moderate cutaneous psoriasis have increased cardiovascular (CV) risk, in absence of CV comorbidities. Our data indicate an imbalance toward the sympathetic arm of the autonomic cardiac modulation. As the increase in sympathetic activity may be associated with a higher CV risk, moderate psoriasis could be considered to be an independent CV risk factor.