Sleep Dysfunction and its Association to Chronic Rhinosinusitis: Updated Review
Background Poor sleep has significant effects on health contributing to increased morbidity and mortality. The direct and indirect costs of sleep dysfunction total well in to the billions of dollars annually in the United States. Chronic rhinosinusitis (CRS) affects up to 16% of the US population an...
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Published in | Laryngoscope investigative otolaryngology Vol. 2; no. 2; pp. 46 - 52 |
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Main Authors | , , |
Format | Journal Article |
Language | English |
Published |
United States
John Wiley & Sons, Inc
01.04.2017
John Wiley and Sons Inc |
Subjects | |
Online Access | Get full text |
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Summary: | Background
Poor sleep has significant effects on health contributing to increased morbidity and mortality. The direct and indirect costs of sleep dysfunction total well in to the billions of dollars annually in the United States. Chronic rhinosinusitis (CRS) affects up to 16% of the US population and has been linked to poor sleep quality with up to three quarters of patients with CRS reporting poor sleep quality. There is a growing body of literature evaluating the relationship between sleep and CRS. In this review, we organize and present the current knowledge on the associations between sleep and CRS as well as identify areas for further investigation.
Data sources
A structured literature search from 1946 to 2016 was conducted in the English language using OVID MEDLINE database, PubMed, and EMBASE.
Review methods
s were reviewed for relevance and appropriate studies were included in the narrative review.
Results
Studies were analyzed and discussed as they pertained to the following categories of CRS and sleep: (1) subjective measures of sleep dysfunction, (2) objective measures of sleep dysfunction, and (3) outcomes on sleep quality following treatment of CRS. Articles on the pathophysiology of sleep dysfunction in CRS were separately reviewed.
Conclusions
An evolving body of research demonstrates that quality of sleep is compromised in the majority of patients with CRS. Following treatment of CRS, there is significant improvement in subjective sleep quality, but additional research investigating objective measures following treatment is still needed. Additionally, further investigation is required to better elucidate the underlying pathophysiology of the relationship between sleep dysfunction and CRS.
Level of Evidence
N/A. |
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Bibliography: | Financial Disclosures: Dr. Jeremiah Alt is supported by a grant from the University of Utah Program in Personalized Health and the National Center for Advancing Translational Sciences of the National Institute of Health under Award Number KL2TR001065. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Health. Dr. Alt is a consultant for Spirox. Drs. Alt and Orlandi are both consultants for Medtronic. Dr, Orlandi is a consultant for Intersect, 480 Biomedical, and BioInspire. Conflict of Interest: None ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 2378-8038 0023-852X 2378-8038 |
DOI: | 10.1002/lio2.60 |