ABA, hydrogen peroxide and nitric oxide signalling in stomatal guard cells

• Published in: Journal of experimental botany Vol. 55; no. 395; pp. 205 - 212
• Main Authors: Desikan, R, Cheung, M.K, Bright, J, Henson, D, Hancock, J.T, Neill, S.J
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Oxford Oxford University Press 01.01.2004; Oxford Publishing Limited (England)
• Subjects: Abscisic acid; Abscisic Acid - pharmacology; Arabidopsis thaliana; Biological and medical sciences; Calcium; cell communication; Cell physiology; cyclic GMP; Enzymes; Fundamental and applied biological sciences. Psychology; Germination - drug effects; Germination - physiology; Guard cells; Hydrogen; hydrogen peroxide; literature reviews; Models, Biological; Molecular and cellular biology; Molecules; NADP (coenzyme); nitrate reductase; nitric oxide; Nitric Oxide - pharmacology; Oxidases; Oxides; Peroxides; Plant Cells; Plant Development; Plant Growth Regulators - pharmacology; Plant Physiological Phenomena; Plant physiology and development; Plants; Plants - drug effects; protein kinases; Reactive Oxygen Species - metabolism; Signal transduction; Signal Transduction - drug effects; Signal Transduction - physiology; signalling; Signalling in Abiotic Stress; stomata; Water and solutes. Absorption, translocation and permeability; water stress; Enzyme; Transferases; Oxidase; 3',5'-GMP; Hydrogen Peroxides; Water stress; Guard cell; Arabidopsis thaliana; Signal transduction; Cruciferae; Nitrate reductase; Protein kinase; Dicotyledones; Sesquiterpenes; Nitric oxide; Angiospermae; Stomatal movement; Abscisic acid; Plant growth substance; Spermatophyta; Oxidoreductases; Phytohormone; Experimental plant
• ISSN: 0022-0957; 1460-2431; 1460-2431
• DOI: 10.1093/jxb/erh033

Increased synthesis and redistribution of the phytohormone abscisic acid (ABA) in response to water deficit stress initiates an intricate network of signalling pathways in guard cells leading to stomatal closure. Despite the large number of ABA signalling intermediates that are known in guard cells, new discoveries are still being made. Recently, the reactive oxygen species hydrogen peroxide (H2O2) and the reactive nitrogen species nitric oxide (NO) have been identified as key molecules regulating ABA-induced stomatal closure in various species. As with many other physiological responses in which H2O2 and NO are involved, stomatal closure in response to ABA also appears to require the tandem synthesis and action of both these signalling molecules. Recent pharmacological and genetic data have identified NADPH oxidase as a source of H2O2, whilst nitrate reductase has been identified as a source of NO in Arabidopsis guard cells. Some signalling components positioned downstream of H2O2 and NO are calcium, protein kinases and cyclic GMP. However, the exact interaction between the various signalling components in response to H2O2 and NO in guard cells remains to be established.