Effectiveness of Hypertension Management Strategies in SPRINT-Eligible US Adults: A Simulation Study
Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long-term impact of 4 hypertension management strategi...
Saved in:
Published in | Journal of the American Heart Association Vol. 13; no. 2; p. e032370 |
---|---|
Main Authors | , , , , , , , , , , , , |
Format | Journal Article |
Language | English |
Published |
England
John Wiley and Sons Inc
16.01.2024
Wiley |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long-term impact of 4 hypertension management strategies in SPRINT-eligible US adults.
The validated Blood Pressure Control-Cardiovascular Disease Policy Model, a discrete event simulation of hypertension care processes (ie, visit frequency, blood pressure [BP] measurement accuracy, medication intensification, and medication adherence) and CVD outcomes, was populated with 25 000 SPRINT-eligible US adults. Four hypertension management strategies were simulated: (1) usual care targeting BP <140/90 mm Hg (Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care), (2) intensive care per the SPRINT protocol targeting BP <120/90 mm Hg (SPRINT intensive), (3) usual care targeting guideline-recommended BP <130/80 mm Hg (American College of Cardiology/American Heart Association usual care), and (4) team-based care added to usual care and targeting BP <130/80 mm Hg. Relative to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, among the 18.1 million SPRINT-eligible US adults, an estimated 138 100 total CVD events could be prevented per year with SPRINT intensive, 33 900 with American College of Cardiology/American Heart Association usual care, and 89 100 with team-based care. Compared with the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, SPRINT intensive care was projected to increase treatment-related serious adverse events by 77 600 per year, American College of Cardiology/American Heart Association usual care by 33 300, and team-based care by 27 200.
As BP control has declined in recent years, health systems must prioritize hypertension management and invest in effective strategies. Adding team-based care to usual care may be a pragmatic way to manage risk in this high-CVD-risk population. |
---|---|
AbstractList | BACKGROUNDDespite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long-term impact of 4 hypertension management strategies in SPRINT-eligible US adults.METHODS AND RESULTSThe validated Blood Pressure Control-Cardiovascular Disease Policy Model, a discrete event simulation of hypertension care processes (ie, visit frequency, blood pressure [BP] measurement accuracy, medication intensification, and medication adherence) and CVD outcomes, was populated with 25 000 SPRINT-eligible US adults. Four hypertension management strategies were simulated: (1) usual care targeting BP <140/90 mm Hg (Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care), (2) intensive care per the SPRINT protocol targeting BP <120/90 mm Hg (SPRINT intensive), (3) usual care targeting guideline-recommended BP <130/80 mm Hg (American College of Cardiology/American Heart Association usual care), and (4) team-based care added to usual care and targeting BP <130/80 mm Hg. Relative to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, among the 18.1 million SPRINT-eligible US adults, an estimated 138 100 total CVD events could be prevented per year with SPRINT intensive, 33 900 with American College of Cardiology/American Heart Association usual care, and 89 100 with team-based care. Compared with the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, SPRINT intensive care was projected to increase treatment-related serious adverse events by 77 600 per year, American College of Cardiology/American Heart Association usual care by 33 300, and team-based care by 27 200.CONCLUSIONSAs BP control has declined in recent years, health systems must prioritize hypertension management and invest in effective strategies. Adding team-based care to usual care may be a pragmatic way to manage risk in this high-CVD-risk population. Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long-term impact of 4 hypertension management strategies in SPRINT-eligible US adults. The validated Blood Pressure Control-Cardiovascular Disease Policy Model, a discrete event simulation of hypertension care processes (ie, visit frequency, blood pressure [BP] measurement accuracy, medication intensification, and medication adherence) and CVD outcomes, was populated with 25 000 SPRINT-eligible US adults. Four hypertension management strategies were simulated: (1) usual care targeting BP <140/90 mm Hg (Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care), (2) intensive care per the SPRINT protocol targeting BP <120/90 mm Hg (SPRINT intensive), (3) usual care targeting guideline-recommended BP <130/80 mm Hg (American College of Cardiology/American Heart Association usual care), and (4) team-based care added to usual care and targeting BP <130/80 mm Hg. Relative to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, among the 18.1 million SPRINT-eligible US adults, an estimated 138 100 total CVD events could be prevented per year with SPRINT intensive, 33 900 with American College of Cardiology/American Heart Association usual care, and 89 100 with team-based care. Compared with the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, SPRINT intensive care was projected to increase treatment-related serious adverse events by 77 600 per year, American College of Cardiology/American Heart Association usual care by 33 300, and team-based care by 27 200. As BP control has declined in recent years, health systems must prioritize hypertension management and invest in effective strategies. Adding team-based care to usual care may be a pragmatic way to manage risk in this high-CVD-risk population. Background Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals have not been adopted in the United States. This study aimed to simulate the potential long‐term impact of 4 hypertension management strategies in SPRINT‐eligible US adults. Methods and Results The validated Blood Pressure Control–Cardiovascular Disease Policy Model, a discrete event simulation of hypertension care processes (ie, visit frequency, blood pressure [BP] measurement accuracy, medication intensification, and medication adherence) and CVD outcomes, was populated with 25 000 SPRINT‐eligible US adults. Four hypertension management strategies were simulated: (1) usual care targeting BP <140/90 mm Hg (Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care), (2) intensive care per the SPRINT protocol targeting BP <120/90 mm Hg (SPRINT intensive), (3) usual care targeting guideline‐recommended BP <130/80 mm Hg (American College of Cardiology/American Heart Association usual care), and (4) team‐based care added to usual care and targeting BP <130/80 mm Hg. Relative to the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, among the 18.1 million SPRINT‐eligible US adults, an estimated 138 100 total CVD events could be prevented per year with SPRINT intensive, 33 900 with American College of Cardiology/American Heart Association usual care, and 89 100 with team‐based care. Compared with the Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure usual care, SPRINT intensive care was projected to increase treatment‐related serious adverse events by 77 600 per year, American College of Cardiology/American Heart Association usual care by 33 300, and team‐based care by 27 200. Conclusions As BP control has declined in recent years, health systems must prioritize hypertension management and invest in effective strategies. Adding team‐based care to usual care may be a pragmatic way to manage risk in this high‐CVD‐risk population. |
Author | Kronish, Ian M Bryant, Kelsey B Weintraub, William S Bress, Adam P Cohen, Jordana B Derington, Catherine G Zhang, Yiyi King, Jordan B Zhang, Fengdi Shea, Steven Sheppard, James P Moran, Andrew E Bellows, Brandon K |
AuthorAffiliation | 7 Department of Medicine Georgetown University Washington DC USA 2 Department of Medicine Mount Sinai New York NY USA 4 Intermountain Healthcare Department of Population Health Sciences University of Utah Salt Lake City UT USA 6 Institute for Health Research Kaiser Permanente Colorado Aurora CO USA 3 Department of Medicine and Department of Biostatistics, Epidemiology, and Informatics University of Pennsylvania Philadelphia PA USA 5 Nuffield Department of Primary Care Health Sciences University of Oxford UK 1 Department of Medicine Columbia University New York NY USA 8 MedStar Health Research Institute Washington DC USA |
AuthorAffiliation_xml | – name: 5 Nuffield Department of Primary Care Health Sciences University of Oxford UK – name: 6 Institute for Health Research Kaiser Permanente Colorado Aurora CO USA – name: 3 Department of Medicine and Department of Biostatistics, Epidemiology, and Informatics University of Pennsylvania Philadelphia PA USA – name: 1 Department of Medicine Columbia University New York NY USA – name: 4 Intermountain Healthcare Department of Population Health Sciences University of Utah Salt Lake City UT USA – name: 2 Department of Medicine Mount Sinai New York NY USA – name: 8 MedStar Health Research Institute Washington DC USA – name: 7 Department of Medicine Georgetown University Washington DC USA |
Author_xml | – sequence: 1 givenname: Fengdi orcidid: 0009-0002-2380-0708 surname: Zhang fullname: Zhang, Fengdi organization: Department of Medicine Columbia University New York NY USA – sequence: 2 givenname: Kelsey B orcidid: 0000-0001-7180-8064 surname: Bryant fullname: Bryant, Kelsey B organization: Department of Medicine Mount Sinai New York NY USA – sequence: 3 givenname: Andrew E orcidid: 0000-0003-3554-0085 surname: Moran fullname: Moran, Andrew E organization: Department of Medicine Columbia University New York NY USA – sequence: 4 givenname: Yiyi orcidid: 0000-0002-8663-5001 surname: Zhang fullname: Zhang, Yiyi organization: Department of Medicine Columbia University New York NY USA – sequence: 5 givenname: Jordana B orcidid: 0000-0003-4649-079X surname: Cohen fullname: Cohen, Jordana B organization: Department of Medicine and Department of Biostatistics, Epidemiology, and Informatics University of Pennsylvania Philadelphia PA USA – sequence: 6 givenname: Adam P orcidid: 0000-0002-2259-5039 surname: Bress fullname: Bress, Adam P organization: Intermountain Healthcare Department of Population Health Sciences University of Utah Salt Lake City UT USA – sequence: 7 givenname: James P orcidid: 0000-0002-4461-8756 surname: Sheppard fullname: Sheppard, James P organization: Nuffield Department of Primary Care Health Sciences University of Oxford UK – sequence: 8 givenname: Jordan B orcidid: 0000-0002-6783-7951 surname: King fullname: King, Jordan B organization: Institute for Health Research Kaiser Permanente Colorado Aurora CO USA – sequence: 9 givenname: Catherine G orcidid: 0000-0001-7382-4607 surname: Derington fullname: Derington, Catherine G organization: Intermountain Healthcare Department of Population Health Sciences University of Utah Salt Lake City UT USA – sequence: 10 givenname: William S orcidid: 0000-0002-5384-5571 surname: Weintraub fullname: Weintraub, William S organization: MedStar Health Research Institute Washington DC USA – sequence: 11 givenname: Ian M orcidid: 0000-0003-0945-2380 surname: Kronish fullname: Kronish, Ian M organization: Department of Medicine Columbia University New York NY USA – sequence: 12 givenname: Steven orcidid: 0000-0002-7382-0603 surname: Shea fullname: Shea, Steven organization: Department of Medicine Columbia University New York NY USA – sequence: 13 givenname: Brandon K orcidid: 0000-0003-1395-6047 surname: Bellows fullname: Bellows, Brandon K organization: Department of Medicine Columbia University New York NY USA |
BackLink | https://www.ncbi.nlm.nih.gov/pubmed/38214272$$D View this record in MEDLINE/PubMed |
BookMark | eNpVkUtP3DAQgKOKqlDKubcqx16y-BXH7qWK0La7FX2ogbPlOOPUKI_FdpD23_S38MtIuhSBL7Zmxt-M5nubHA3jAEnyHqMVxhyffys35QoTukKU0AK9Sk4IYkUmpUBHz97HyVkIN2g-nBQ0l2-SYyoIZqQgJwmsrQUT3R0MEEI62nSz34GPMAQ3Dul3PegWehhiWkWvI7QOQuqGtPr1e_vjKlt3rnV1B-l1lZbN1MXwKS3v_1aunzodF0IVp2b_LnltdRfg7PE-Ta6_rK8uNtnlz6_bi_IyM4yjmEmKQRomiCWkkJbmhnJmG1xYblhNhNTCCoNqgW1dMF0DxzXWAmouWcGIoKfJ9sBtRn2jdt712u_VqJ36Fxh9q7SPznSgCs45MwLlDaeMWDpD541xBrUEmXMysz4fWLup7qEx8w687l5AX2YG90e1453CSBIu0EL4-Ejw4-0EIareBQNdpwcYp6CIxHleYMyWwc8PpcaPIXiwT30wUotstchWs2x1kD3_-PB8vKf6_2rpA8xLpqw |
CitedBy_id | crossref_primary_10_1152_ajpheart_00052_2024 |
Cites_doi | 10.1161/01.CIR.0000017861.00991.2F 10.1161/CIRCULATIONAHA.113.004046 10.1016/j.amjcard.2010.09.026 10.1016/j.jacc.2019.03.529 10.1093/aje/kwy139 10.1016/S0140-6736(15)00805-3 10.1161/CIRCHEARTFAILURE.115.002460 10.1161/CIRCOUTCOMES.118.005624 10.1001/jamacardio.2019.6192 10.1001/jama.2016.7050 10.1093/ije/dyy264 10.1016/S0149-2918(01)80109-0 10.1161/CIRCULATIONAHA.116.025322 10.1001/jamacardio.2021.3508 10.3310/hta7310 10.1161/JAHA.120.016174 10.1161/CIR.0000000000000758 10.1016/S0140-6736(15)01225-8 10.7326/M17-1805 10.1177/0272989X06290495 10.1001/jamainternmed.2020.0051 10.1001/jama.289.19.2560 10.1136/bmj.39553.670231.25 10.1093/ajh/hpad047 10.1161/HYPERTENSIONAHA.109.148791 10.1161/HYPERTENSIONAHA.122.20292 10.1016/j.amepre.2014.03.004 10.1161/CIRCULATIONAHA.120.051683 10.3399/BJGP.2022.0389 10.1001/jamanetworkopen.2021.43001 10.1016/S0140-6736(12)61689-4 10.1093/ajh/hpy053 10.1136/bmj.326.7404.1427 10.1161/CIRCULATIONAHA.113.007787 10.1371/journal.pmed.1004223 10.1056/NEJMsa1616035 10.1016/j.cardfail.2019.07.134 10.1161/01.CIR.0000109691.16944.DA 10.1111/jgs.16749 10.1161/JAHA.120.020361 10.1056/NEJMoa1717250 10.1161/CIRCULATIONAHA.113.004042 10.1161/CIRCULATIONAHA.118.038165 10.1038/s41371-023-00811-3 10.1161/HYP.0000000000000065 10.1016/j.jchf.2016.02.007 10.1161/JAHA.120.019707 10.1001/jamacardio.2016.3517 10.1016/j.jacc.2021.02.058 10.1056/NEJMoa1511939 |
ContentType | Journal Article |
Copyright | 2024 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. |
Copyright_xml | – notice: 2024 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. |
DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 7X8 5PM DOA |
DOI | 10.1161/JAHA.123.032370 |
DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef MEDLINE - Academic PubMed Central (Full Participant titles) Directory of Open Access Journals |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef MEDLINE - Academic |
DatabaseTitleList | MEDLINE - Academic MEDLINE |
Database_xml | – sequence: 1 dbid: DOA name: Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine |
DocumentTitleAlternate | Management Strategies in SPRINT‐Eligible US Adults |
EISSN | 2047-9980 |
EndPage | e032370 |
ExternalDocumentID | oai_doaj_org_article_76664c805d6342f3b8120464eb9e9562 10_1161_JAHA_123_032370 38214272 |
Genre | Journal Article |
GeographicLocations | United States |
GeographicLocations_xml | – name: United States |
GrantInformation_xml | – fundername: NHLBI NIH HHS grantid: K01 HL140170 – fundername: NHLBI NIH HHS grantid: R01 HL157439 – fundername: NHLBI NIH HHS grantid: R01 HL152699 – fundername: NIA NIH HHS grantid: K24 AG080168 – fundername: NHLBI NIH HHS grantid: R01 HL130500 – fundername: NIA NIH HHS grantid: R01 AG065805 – fundername: NHLBI NIH HHS grantid: R01 HL158790 – fundername: Royal Society via a Sir Henry Dale Fellowship grantid: 211182/Z/18/Z |
GroupedDBID | 0R~ 1OC 24P 53G 5VS 8-1 AAZKR ACGFO ACXQS ADBBV ADKYN ADZMN AEGXH AENEX AIAGR ALAGY ALMA_UNASSIGNED_HOLDINGS AOIJS AVUZU BAWUL BCNDV CGR CUY CVF DIK EBS ECM EIF EMOBN GODZA GROUPED_DOAJ GX1 HYE KQ8 M48 M~E NPM OK1 RAH RHF RNS RPM WIN AAYXX CITATION 7X8 5PM |
ID | FETCH-LOGICAL-c460t-931e9c482f2279f35c364fd17f6c4b289a8f8c0b81fb74abe61b1a8eb69474283 |
IEDL.DBID | RPM |
ISSN | 2047-9980 |
IngestDate | Tue Oct 22 15:14:57 EDT 2024 Tue Sep 17 21:29:10 EDT 2024 Thu Oct 24 20:33:08 EDT 2024 Fri Dec 06 02:10:21 EST 2024 Sat Nov 02 12:27:26 EDT 2024 |
IsDoiOpenAccess | true |
IsOpenAccess | true |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Keywords | blood pressure hypertension cardiovascular diseases |
Language | English |
License | This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c460t-931e9c482f2279f35c364fd17f6c4b289a8f8c0b81fb74abe61b1a8eb69474283 |
Notes | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 This manuscript was sent to Tazeen H. Jafar, MD MPH, Associate Editor, for review by expert referees, editorial decision, and final disposition. For Sources of Funding and Disclosures, see page 9. Supplemental Material is available at https://www.ahajournals.org/doi/suppl/10.1161/JAHA.123.032370 |
ORCID | 0009-0002-2380-0708 0000-0001-7180-8064 0000-0001-7382-4607 0000-0003-3554-0085 0000-0002-4461-8756 0000-0002-6783-7951 0000-0003-0945-2380 0000-0003-4649-079X 0000-0002-5384-5571 0000-0002-2259-5039 0000-0002-8663-5001 0000-0002-7382-0603 0000-0003-1395-6047 |
OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10926802/ |
PMID | 38214272 |
PQID | 2915571148 |
PQPubID | 23479 |
ParticipantIDs | doaj_primary_oai_doaj_org_article_76664c805d6342f3b8120464eb9e9562 pubmedcentral_primary_oai_pubmedcentral_nih_gov_10926802 proquest_miscellaneous_2915571148 crossref_primary_10_1161_JAHA_123_032370 pubmed_primary_38214272 |
PublicationCentury | 2000 |
PublicationDate | 2024-01-16 |
PublicationDateYYYYMMDD | 2024-01-16 |
PublicationDate_xml | – month: 01 year: 2024 text: 2024-01-16 day: 16 |
PublicationDecade | 2020 |
PublicationPlace | England |
PublicationPlace_xml | – name: England – name: Hoboken |
PublicationTitle | Journal of the American Heart Association |
PublicationTitleAlternate | J Am Heart Assoc |
PublicationYear | 2024 |
Publisher | John Wiley and Sons Inc Wiley |
Publisher_xml | – name: John Wiley and Sons Inc – name: Wiley |
References | e_1_3_1_43_2 e_1_3_1_22_2 e_1_3_1_45_2 e_1_3_1_24_2 e_1_3_1_8_2 e_1_3_1_41_2 e_1_3_1_20_2 e_1_3_1_4_2 e_1_3_1_6_2 e_1_3_1_26_2 e_1_3_1_47_2 e_1_3_1_2_2 e_1_3_1_28_2 e_1_3_1_49_2 e_1_3_1_32_2 e_1_3_1_34_2 e_1_3_1_13_2 e_1_3_1_51_2 e_1_3_1_11_2 e_1_3_1_30_2 e_1_3_1_17_2 e_1_3_1_15_2 e_1_3_1_36_2 e_1_3_1_19_2 e_1_3_1_38_2 e_1_3_1_21_2 e_1_3_1_44_2 e_1_3_1_23_2 e_1_3_1_46_2 e_1_3_1_7_2 e_1_3_1_40_2 e_1_3_1_9_2 e_1_3_1_42_2 e_1_3_1_29_2 e_1_3_1_3_2 e_1_3_1_5_2 e_1_3_1_25_2 e_1_3_1_48_2 e_1_3_1_27_2 e_1_3_1_33_2 e_1_3_1_35_2 e_1_3_1_12_2 e_1_3_1_50_2 e_1_3_1_10_2 e_1_3_1_31_2 e_1_3_1_52_2 e_1_3_1_16_2 e_1_3_1_14_2 e_1_3_1_37_2 e_1_3_1_18_2 e_1_3_1_39_2 |
References_xml | – ident: e_1_3_1_39_2 doi: 10.1161/01.CIR.0000017861.00991.2F – ident: e_1_3_1_29_2 doi: 10.1161/CIRCULATIONAHA.113.004046 – ident: e_1_3_1_38_2 doi: 10.1016/j.amjcard.2010.09.026 – ident: e_1_3_1_20_2 doi: 10.1016/j.jacc.2019.03.529 – ident: e_1_3_1_30_2 doi: 10.1093/aje/kwy139 – ident: e_1_3_1_23_2 doi: 10.1016/S0140-6736(15)00805-3 – ident: e_1_3_1_42_2 doi: 10.1161/CIRCHEARTFAILURE.115.002460 – ident: e_1_3_1_16_2 doi: 10.1161/CIRCOUTCOMES.118.005624 – ident: e_1_3_1_45_2 doi: 10.1001/jamacardio.2019.6192 – ident: e_1_3_1_49_2 doi: 10.1001/jama.2016.7050 – ident: e_1_3_1_19_2 doi: 10.1093/ije/dyy264 – ident: e_1_3_1_36_2 doi: 10.1016/S0149-2918(01)80109-0 – ident: e_1_3_1_5_2 doi: 10.1161/CIRCULATIONAHA.116.025322 – ident: e_1_3_1_7_2 – ident: e_1_3_1_31_2 doi: 10.1001/jamacardio.2021.3508 – ident: e_1_3_1_33_2 doi: 10.3310/hta7310 – ident: e_1_3_1_51_2 doi: 10.1161/JAHA.120.016174 – ident: e_1_3_1_24_2 doi: 10.1161/CIR.0000000000000758 – ident: e_1_3_1_32_2 doi: 10.1016/S0140-6736(15)01225-8 – ident: e_1_3_1_12_2 doi: 10.7326/M17-1805 – ident: e_1_3_1_25_2 doi: 10.1177/0272989X06290495 – ident: e_1_3_1_46_2 doi: 10.1001/jamainternmed.2020.0051 – ident: e_1_3_1_21_2 doi: 10.1001/jama.289.19.2560 – ident: e_1_3_1_37_2 doi: 10.1136/bmj.39553.670231.25 – ident: e_1_3_1_6_2 doi: 10.1093/ajh/hpad047 – ident: e_1_3_1_35_2 doi: 10.1161/HYPERTENSIONAHA.109.148791 – ident: e_1_3_1_11_2 doi: 10.1161/HYPERTENSIONAHA.122.20292 – ident: e_1_3_1_13_2 doi: 10.1016/j.amepre.2014.03.004 – ident: e_1_3_1_18_2 doi: 10.1161/CIRCULATIONAHA.120.051683 – ident: e_1_3_1_9_2 doi: 10.3399/BJGP.2022.0389 – ident: e_1_3_1_22_2 doi: 10.1001/jamanetworkopen.2021.43001 – ident: e_1_3_1_26_2 doi: 10.1016/S0140-6736(12)61689-4 – ident: e_1_3_1_52_2 doi: 10.1093/ajh/hpy053 – ident: e_1_3_1_34_2 doi: 10.1136/bmj.326.7404.1427 – ident: e_1_3_1_43_2 doi: 10.1161/CIRCULATIONAHA.113.007787 – ident: e_1_3_1_50_2 doi: 10.1371/journal.pmed.1004223 – ident: e_1_3_1_3_2 doi: 10.1056/NEJMsa1616035 – ident: e_1_3_1_40_2 doi: 10.1016/j.cardfail.2019.07.134 – ident: e_1_3_1_41_2 doi: 10.1161/01.CIR.0000109691.16944.DA – ident: e_1_3_1_48_2 doi: 10.1111/jgs.16749 – ident: e_1_3_1_44_2 doi: 10.1161/JAHA.120.020361 – ident: e_1_3_1_15_2 doi: 10.1056/NEJMoa1717250 – ident: e_1_3_1_28_2 doi: 10.1161/CIRCULATIONAHA.113.004042 – ident: e_1_3_1_14_2 doi: 10.1161/CIRCULATIONAHA.118.038165 – ident: e_1_3_1_17_2 doi: 10.1038/s41371-023-00811-3 – ident: e_1_3_1_10_2 doi: 10.1161/HYP.0000000000000065 – ident: e_1_3_1_27_2 doi: 10.1016/j.jchf.2016.02.007 – ident: e_1_3_1_47_2 doi: 10.1161/JAHA.120.019707 – ident: e_1_3_1_4_2 doi: 10.1001/jamacardio.2016.3517 – ident: e_1_3_1_8_2 doi: 10.1016/j.jacc.2021.02.058 – ident: e_1_3_1_2_2 doi: 10.1056/NEJMoa1511939 |
SSID | ssj0000627359 |
Score | 2.3879364 |
Snippet | Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood pressure goals... BACKGROUNDDespite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood... Background Despite reducing cardiovascular disease (CVD) events and death in SPRINT (Systolic Blood Pressure Intervention Trial), intensive systolic blood... |
SourceID | doaj pubmedcentral proquest crossref pubmed |
SourceType | Open Website Open Access Repository Aggregation Database Index Database |
StartPage | e032370 |
SubjectTerms | Adult Antihypertensive Agents - pharmacology Antihypertensive Agents - therapeutic use Blood Pressure cardiovascular diseases Cardiovascular Diseases - epidemiology Humans hypertension Hypertension - diagnosis Hypertension - drug therapy Hypertension - epidemiology Original Research Risk Factors United States - epidemiology |
SummonAdditionalLinks | – databaseName: Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3BTtwwELUQh6oXBG2BhRa5EgcuAcd2bKe3bQVaIcEFVuJmxY4NK0EWscuBG5_AJ_At_ZR-SWfiLOyiSlx6TWLFmpfMvLHHbwjZjVzXNfchCwBvJisuMojzMVNFzaVhkWmHh5NPTtVgKI8viou5Vl9YE5bkgZPhDjTwa-kNK2olJI_CQUTC7bjgygDcPnlfxueSqeSDISwXZaflA6zm4Lg_wIU_sc8EF9iaeC4MtWr9_6KYbysl50LP0SpZ6Tgj7ae5rpGl0HwiH066XfHP5DJJEHd-i44jHUB2edfWpo8b-lrhQmdatGFCRw1tSyHO_zw-HWJZsrsOdHhG-yjIMflB-7-fz0Y3XXMviuWGD1_I8Ojw_Ncg6xooZF4qNs1KkYfSS8Mj6gRGUXihZKxzHZWXDlKtykTjGZg0Oi0rF1Tu8soEp0qpUYltnSw34yZsEupL7itgd0rFXOoYDCthFKvrGhABz9AjezN72tukk2Hb_ELlFk1vwfQ2mb5HfqK9Xx5Dgev2AsBuO9jte7D3yPcZWhZ-CNzlqJowvp9Yjor3GtO8HtlI6L28ShhUmNMw2izgujCXxTvN6KoV3c5ZyZVhfOt_zH6bfORAjnApJ1dfyfL07j58A3IzdTvtd_wX9a_2TA priority: 102 providerName: Directory of Open Access Journals – databaseName: Scholars Portal Open Access Journals dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwdV3bbtQwELVQkaq-IO6Em4zEAy8pvsV2kBBaUKtVpeWlXalvVuzYsFJJYHcr0b_hW_gyZhJvy6LlNYnjyMfjmWNPzhDyOgnTtiLEMgK8pWqELMHPp1JXrVCWJWY8_pw8-6ync3VyXp3flAPKA7jaSe2wntR8eXH488fVBzD494PBa_72ZDLFPT15yKSQBvj7bQFuEfO7ZjnWH5dl8NRVneV9drQ7IPvSogKZEVtOatDy3xWA_ptH-ZdjOr5L7uSIkk7GKXCP3IrdfbI_y2fmD0gcBYrzqkb7RKfAPZdD5nrf0Zv8F7pRqo0ruujokChxVh5hyrK_iHR-Sico1rF6Rye_f50uvuXCXxRTEa8ekvnx0dmnaZmLK5RBabYua8ljHZQVCTUEk6yC1Cq13CQdlAca1thkA_OWJ29U46Pmnjc2el0rgyptj8he13fxCaGhFqGByE_rxJVJ0bIaWrG2baWHeFQW5M1mNN33UUPDDdxDc4cYOMDAjRgU5COO9vVjKH49XOiXX1y2JWeAcqlgWdVqqUSCTrjAE9ro6wh0TxTk1QYrB8aCJyBNF_vLlROohm-QAhbk8YjddVcb7Atit1Dd-pbtO93i6yDIzVkttGXi6X9f-owcCIiGcO-G6-dkb728jC8gmln7l8Ms_QN6H_AY priority: 102 providerName: Scholars Portal |
Title | Effectiveness of Hypertension Management Strategies in SPRINT-Eligible US Adults: A Simulation Study |
URI | https://www.ncbi.nlm.nih.gov/pubmed/38214272 https://search.proquest.com/docview/2915571148 https://pubmed.ncbi.nlm.nih.gov/PMC10926802 https://doaj.org/article/76664c805d6342f3b8120464eb9e9562 |
Volume | 13 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV27btswFCWSDEWXou-qj4AFOnSRzZdIqpsbJDACuCiQGMhGiBSZGoilwHaGbPmEfkK_pZ-SL8klJaVx0amLBkkEBR6K91zy8BChT4GpumbO5x7gzUXFeA5xPuSyqJnQJBBl4-bk2Tc5nYvjs-JsB8lhL0wS7Tu7GDUXy1Gz-JG0lZdLNx50YuPvswNKSiY1YeNdtAvx90GO3o2_EJKLsvfxAUYzPp5M46QfHxHOuIqHv3EdrcYU24pGybT_X0zzb8Hkgwh09BQ96akjnnSf-Azt-OY5ejTrF8dfoPPOibgfvnAb8BSSzFWSqLcN_iN0wYMlrV_jRYOTIuL09ubnYVQn2wuP5yd4En051l_w5Pevk8WyP-MLR9Xh9Us0Pzo8PZjm_TkKuROSbPKSU186oVmIdoGBF45LEWqqgnTCQsZV6aAdsZoGq0RlvaSWVtpbWQoVDdleob2mbfwbhF3JXAUkT8pAhQpekxJKkbquuQXqyTP0eWhPc9nZZZiUZkhqIgoGUDAdChn6Gtv7_rXoc51utKtz06NtFGRXwmlS1JILFqASyuJirLelh8yOZejjgJaB_yIudlSNb6_WhkXjexWzvQy97tC7r2pAP0N6C9etb9l-Al0xeW8PXe_t_xd9hx4zYEZxHofK92hvs7ryH4DZbOx-mhGA60zo_dSp7wBTAfqe |
link.rule.ids | 230,314,727,780,784,864,885,2102,24318,27924,27925,53791,53793 |
linkProvider | National Library of Medicine |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LbtQwFL0qRQI2iDfhaSQWbDLjV2yH3VC1CqVTIXVG6s6KHbuM1EmqmemCHZ_AJ_AtfApfgp1H6SBWbJNYtnwc33Pt42OAt57KqqLWpS7Am_KSsjTEeZ-KrKJcYY-liYeTp8eimPPD0-x0B8RwFqYV7VuzGNXny1G9-NJqKy-WdjzoxMafp3sE51QoTMc34GbGZE6uZendDByCcpb3Tj6B04wPJ0Vc9mMjzCiT8fo3pqLZmKRb8ai17f8X1_xbMnktBh3cg7s9eUSTrpH3YcfVD-DWtN8efwhnnRdxP4GhxqMipJmrVqTe1OiP1AUNprRujRY1ajURs1_fvu9HfbI5d2h-gibRmWP9Hk1-_jhZLPtbvlDUHX59BPOD_dlekfY3KaSWC7xJc0ZcbrmiPhoGepZZJriviPTCchNyrlJ5ZbFRxBvJS-MEMaRUzoicy2jJ9hh266Z2TwHZnNoy0DwhPOHSO4XzUApXVcVMIJ8sgXdDf-qLzjBDt4mGIDqioAMKukMhgQ-xv68-i07X7YNmdaZ7vLUM-RW3CmeVYJz6UAmhcTvWmdyF3I4m8GZAS4c_I253lLVrLteaRut7GfO9BJ506F1VNaCfgNrCdast22_CYGzdt4fB9-z_i76G28VseqSPPh5_eg53aOBJcVWHiBewu1ldupeB52zMq3ZQ_wbboPwk |
linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3LbtQwFLWgSBUbRHmGtmAkFmwy8Su2w24oHQ2FqSq1I3Vnxa8yUicZzUwX3fEJfALfwqf0S7DzKB3Eim0Sy1bOje-59skxAO88EdYS41IX4E1ZSWga8rxPeW4Jk8gjoePPyZNjPp6yo_P8vFNVrjpZZWX0bFBdzgfV7FujrVzMTdbrxLKTyQFGBeESkWxhfXYfPMhpiLI7lXo7C4fEnBedm0_gNdnRcByX_ugAUUJFPAKOymg4JshGTmqs-__FN_-WTd7JQ6PH4FFHIOGwHegOuOeqJ2B70m2RPwUXrR9xN4nB2sNxKDWXjVC9ruAfuQvsjWndCs4q2Ogizm6-_ziMGmV96eD0FA6jO8fqAxz--nk6m3cnfcGoPbx-Bqajw7ODcdqdppAaxtE6LSh2hWGS-Gga6GluKGfeYuG5YTrUXaX00iAtsdeCldpxrHEpneYFE9GW7TnYqurKvQTQFMSUgepx7jET3klUhFbIWkt1IKA0Ae_796kWrWmGaooNjlVEQQUUVItCAj7G9337WHS7bi7UywvVYa5EqLGYkSi3nDLiQyeYxC1ZpwsX6juSgLc9Wip8HXHLo6xcfbVSJNrfi1jzJeBFi95tVz36CZAbuG6MZfNOCMjGgbsPwFf_3_QN2D75NFJfPx9_2QUPSaBKcWEH8z2wtV5euf1Addb6dRPTvwF8b_03 |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Effectiveness+of+Hypertension+Management+Strategies+in+SPRINT-Eligible+US+Adults%3A+A%C2%A0Simulation+Study&rft.jtitle=Journal+of+the+American+Heart+Association&rft.au=Zhang%2C+Fengdi&rft.au=Bryant%2C+Kelsey+B&rft.au=Moran%2C+Andrew+E&rft.au=Zhang%2C+Yiyi&rft.date=2024-01-16&rft.eissn=2047-9980&rft.volume=13&rft.issue=2&rft.spage=e032370&rft_id=info:doi/10.1161%2FJAHA.123.032370&rft_id=info%3Apmid%2F38214272&rft.externalDocID=38214272 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2047-9980&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2047-9980&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2047-9980&client=summon |