Development of a reliable and reproducible phantom manufacturing method using silica microspheres in silicone
Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. So...
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Published in | Journal of biomedical optics Vol. 22; no. 9; p. 095004 |
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Main Authors | , |
Format | Journal Article |
Language | English |
Published |
United States
Society of Photo-Optical Instrumentation Engineers
01.09.2017
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Subjects | |
Online Access | Get full text |
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Summary: | Optically scattering phantoms composed of silica microspheres embedded in an optically clear silicone matrix were manufactured using a previously developed method. Multiple problems, such as sphere aggregation, adsorption to the cast, and silicone shrinkage, were, however, frequently encountered. Solutions to these problems were developed and an improved method, incorporating these solutions, is presented. The improved method offers excellent reliability and reproducibility for creating phantoms with uniform scattering coefficient. We also present evidence of decreased sphere aggregation. |
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Bibliography: | ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23 |
ISSN: | 1083-3668 1560-2281 |
DOI: | 10.1117/1.JBO.22.9.095004 |