Diffuse non-midline glioma with H3F3A K27M mutation: a prognostic and treatment dilemma

• Published in: Acta neuropathologica communications Vol. 5; no. 1; pp. 38 - 3
• Main Authors: López, Giselle, Oberheim Bush, Nancy Ann, Berger, Mitchel S, Perry, Arie, Solomon, David A
• Format: Journal Article
• Language: English
• Published: England BioMed Central 15.05.2017; BMC
• Subjects: Brain - diagnostic imaging; Brain - pathology; Brain - surgery; Brain cancer; Brain Neoplasms - diagnosis; Brain Neoplasms - genetics; Brain Neoplasms - pathology; Brain Neoplasms - therapy; Classification; Diffuse Glioma; Eosinophilic Granular Body; Female; Glioma; Glioma - diagnosis; Glioma - genetics; Glioma - pathology; Glioma - therapy; Histones - genetics; Humans; IDH1 R132H; K27M Mutation; Kinases; Letter to the Editor; Midline Structure; Mutation; Pediatrics; Prognosis; Proteins; Spinal cord; Tumors; Young Adult

Authors' contributions MSB provided neurosugical management. NAOB provided neuro-oncology management. GL, AP, and DAS performed pathologic assessment. DAS performed genomic analysis. GL and DAS wrote the manuscript and created the figures. All authors read and approved the final manuscript. Com...