The immunological classification of acute lymphoblastic leukemias

The main methods used in order to assess the immunological markers on the blast cells from patients with acute lymphoblastic leukemia (ALL) are critically evaluated. The classification of ALL according to the phenotype of the leukemic cells and their presumed origin is reviewed. The correlations wit...

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Bibliographic Details
Published inCancer Vol. 42; no. S2; pp. 817 - 827
Main Authors Brouet, J. C., Seligmann, M.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 01.08.1978
Subjects
Adolescent
Adult
Aged
Antigens, Neoplasm
B-Lymphocytes - immunology
Child
Child, Preschool
Female
Hematopoietic Stem Cells - immunology
Humans
Immunoglobulin Fc Fragments
Immunoglobulin M
Infant
Leukemia, Lymphoid - classification
Leukemia, Lymphoid - immunology
Leukemia, Lymphoid - therapy
Male
Middle Aged
Prognosis
Receptors, Antigen, B-Cell
Remission, Spontaneous
Rosette Formation
T-Lymphocytes - immunology
Time Factors
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Summary:The main methods used in order to assess the immunological markers on the blast cells from patients with acute lymphoblastic leukemia (ALL) are critically evaluated. The classification of ALL according to the phenotype of the leukemic cells and their presumed origin is reviewed. The correlations with clinical features and prognosis, as well as their possible therapeutic implications, are discussed.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(197808)42:2+<817::AID-CNCR2820420703>3.0.CO;2-2