Contribution of the motor system to the perception of reachable space: an fMRI study

• Published in: The European journal of neuroscience Vol. 40; no. 12; pp. 3807 - 3817
• Main Authors: Bartolo, Angela, Coello, Yann, Edwards, Martin G., Delepoulle, Samuel, Endo, Satoshi, Wing, Alan M.
• Format: Journal Article
• Language: English
• Published: Oxford Blackwell Publishing Ltd 01.12.2014; Blackwell; Wiley
• Subjects: Adult; Biological and medical sciences; Brain - physiology; Brain Mapping; Eye and associated structures. Visual pathways and centers. Vision; Female; Fundamental and applied biological sciences. Psychology; Hand; human vision; Humanities and Social Sciences; Humans; Judgment - physiology; Magnetic Resonance Imaging; Male; motor representation; Neural Pathways; Neuropsychological Tests; peripersonal space; Photic Stimulation; Psychology; Psychomotor Performance - physiology; simulation; Space Perception - physiology; spatial perception; Vertebrates: nervous system and sense organs; Human; peripersonal space; motor representation; Vision; simulation; Space perception; spatial perception; Nuclear magnetic resonance imaging; human vision; Functional imaging; ACL
• ISSN: 0953-816X; 1460-9568
• DOI: 10.1111/ejn.12742

The present functional magnetic resonance imaging (fMRI) study investigates the neural correlates of reachability judgements. In a block design experiment, 14 healthy participants judged whether a visual target presented at different distances in a virtual environment display was reachable or not with the right hand. In two control tasks, they judged the colour or the relative position of the visual target according to flankers. Contrasting the activations registered in the reachability judgement task and in the control tasks, we found activations in the frontal structures, and in the bilateral inferior and superior parietal lobe, including the precuneus, and the bilateral cerebellum. This fronto‐parietal network including the cerebellum overlaps with the brain network usually activated during actual motor production and motor imagery. In a following event‐related design experiment, we contrasted brain activations when targets were rated as ‘reachable’ with those when they were rated as ‘unreachable’. We found activations in the left premotor cortex, the bilateral frontal structures, and the left middle temporal gyrus. At a lower threshold, we also found activations in the left motor cortex, and in the bilateral cerebellum. Given that reaction time increased with target distance in reachable space, we performed a subsequent parametric analysis that revealed a related increase of activity in the fronto‐parietal network including the cerebellum. Unreachable targets did not show similar activation, and particularly in regions associated to motor production and motor imagery. Taken together, these results suggest that dynamical motor representations used to determine what is reachable are also part of the perceptual process leading to the distinct representation of peripersonal and extrapersonal spaces. This fMRI study showed a specific activation in a fronto‐parietal network including the cerebellum for objects in peripersonal space when performing a reachability judgement task with respect to a colour or a spatial control discrimination task.