Comparison of two surgical approaches for treating vitiligo: a preliminary study
Background Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed. Aim To compare the efficacy and side‐effects of two surgical methods (suction blister vs. thin split‐thickness graft technique) for the treatment of vitiligo...
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Published in | International journal of dermatology Vol. 41; no. 3; pp. 135 - 138 |
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Main Authors | , , , , , , |
Format | Journal Article |
Language | English |
Published |
Oxford, UK
Blackwell Science Ltd
01.03.2002
Blackwell Science Blackwell Publishing Ltd |
Subjects | |
Online Access | Get full text |
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Summary: | Background Surgical techniques have recently been introduced for patients with vitiligo. Randomized controlled trials have not been performed.
Aim To compare the efficacy and side‐effects of two surgical methods (suction blister vs. thin split‐thickness graft technique) for the treatment of vitiligo.
Methods Three suction blisters, approximately 0.8 cm in diameter, made with a special tool attached to a vacuum extractor, which were converted to erosions by removal of the roofs of the bullae, and one round erosion of approximately the same diameter, made using a silver knife, were created. One roof of a blister and two cutaneous thin split‐thickness grafts taken from the gluteal region were transferred onto recipient vitiliginous areas; one was left alone. The results were evaluated by one non‐blind and two blind observers bimonthly during the 3‐month follow‐up period.
Results Repigmentation rates were 25–65% in the suction blister technique and 90% in the thin split‐thickness graft technique (P < 0.001).
Conclusions The thin split‐thickness graft technique is superior to the suction blister technique in treating vitiligo. |
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Bibliography: | istex:4D820EE5AF715CBE67357A1814348F12247CEC7D ark:/67375/WNG-1F0QTC0Q-N ArticleID:IJD1391 ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 |
ISSN: | 0011-9059 1365-4632 |
DOI: | 10.1046/j.1365-4362.2002.01391.x |