Cardio-ankle vascular index (CAVI) for the monitoring of the atherosclerosis after heart transplantation

• Published in: Biomedicine & pharmacotherapy Vol. 59; pp. S177 - S179
• Main Authors: Yambe, T., Meng, X., Hou, X., Wang, Q., Sekine, K., Shiraishi, Y., Watanabe, M., Yamaguchi, T., Shibata, M., Kuwayama, T., Maruyama, M., Konno, S., Nitta, S.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Paris Elsevier SAS 01.10.2005; Elsevier
• Subjects: Adolescent; Adult; Ankle - blood supply; Atherosclerosis; Atherosclerosis (general aspects, experimental research); Atherosclerosis - physiopathology; baPWV; Biological and medical sciences; Blood and lymphatic vessels; Brachial Artery - physiology; Cardio-ankle vascular index (CAVI); Cardiology. Vascular system; Female; Heart - physiology; Heart transplantation; Heart Transplantation - physiology; Humans; Male; Medical sciences; Middle Aged; Pharmacology. Drug treatments; Pulse wave velocity (PWV); Regional Blood Flow - physiology; Cardio-ankle vascular index (CAVI); baPWV; Heart transplantation; Atherosclerosis; Pulse wave velocity (PWV); Heart; Cardiovascular disease; Index; Arterial pulse; Transplantation; Velocity; Vascular disease; Ankle; Treatment; Surveillance; Surgery; Blood vessel; Graft; Circulatory system
• ISSN: 0753-3322; 1950-6007
• DOI: 10.1016/S0753-3322(05)80028-9

Atherosclerosis has been reported to progress rapidly after heart transplantation. A quantitative diagnosis is required for the diagnosis of atherosclerosis after heart transplantation. In this study, we compared brachial-ankle pulse wave velocity (baPWV) and cardio-ankle vascular index (CAVI) for the diagnosis. The average values of both baPWV and CAVI in the seven cases after heart transplantation were found to be signif-icantly large in comparison to the average values of the normal healthy people of the same age group. When comparisons were made before and after the heart transplantation in a particular case, CAVI was stable and baPWV changed sharply. A lot of parameters such as blood pressure, blood volume, etc. have been reported to influence baPWV. The results of this study suggested that CAVI was a stable parameter in comparison to baPWV even after heart transplantation. Thus, CAVI may be useful in the diagnosis of arteriosclerosis after heart transplantation.