Central Roles and Regulatory Mechanisms of Dual-Specificity MAPK Phosphatases in Developmental and Stress Signaling

Mitogen-Activated Protein Kinase (MAPK) cascades are conserved signaling modules that integrate multiple signaling pathways. One level of control on the activity of MAPKs is through their negative regulators, MAPK phosphatases (MKPs). Therefore, MKPs also play an integrative role for plants respondi...

Full description

Saved in:
Bibliographic Details
Published inFrontiers in plant science Vol. 9; p. 1697
Main Authors Jiang, Lingyan, Chen, Yinhua, Luo, Lijuan, Peck, Scott C
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 20.11.2018
Subjects
development
mitogen-activated protein kinase
phosphatase
Plant Science
regulatory mechanism
stress signaling
mitogen-activated protein kinase
development
phosphatase
regulatory mechanism
stress signaling
Online AccessGet full text

Cover

More Information
Summary:Mitogen-Activated Protein Kinase (MAPK) cascades are conserved signaling modules that integrate multiple signaling pathways. One level of control on the activity of MAPKs is through their negative regulators, MAPK phosphatases (MKPs). Therefore, MKPs also play an integrative role for plants responding to diverse environmental stimulus; but the mechanism(s) by which these phosphatases contribute to specific signals remains largely unknown. In this review, we summarize recent advances in characterizing the biological functions of a sub-class of MKPs, dual-specificity phosphatases (DSPs), ranging from controlling plant growth and development to modulating stress adaptation. We also discuss putative regulatory mechanisms of DSP-type MKPs, which plants may use to control the correct level of responses at the right place and time. We highlight insights into potential regulation of cross-talk between different signaling pathways, facilitating the development of strategies for targeting such cross-talk and to help improve plant resistance against adverse environmental conditions without affecting the growth and development.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
content type line 23
ObjectType-Review-1
This article was submitted to Plant Microbe Interactions, a section of the journal Frontiers in Plant Science
Reviewed by: Saijaliisa Kangasjärvi, University of Turku, Finland; Alois Schweighofer, Universität Wien, Austria
Edited by: Simone Ferrari, La Sapienza University of Rome, Italy
ISSN:1664-462X
1664-462X
DOI:10.3389/fpls.2018.01697