Reduction in Serine Protease Activity Correlates with Improved Rosacea Severity in a Small, Randomized Pilot Study of a Topical Serine Protease Inhibitor

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Bibliographic Details
Published inJournal of investigative dermatology Vol. 134; no. 4; pp. 1143 - 1145
Main Authors Two, Aimee M., Hata, Tissa R., Nakatsuji, Teruaki, Coda, Alvin B., Kotol, Paul F., Wu, Wiggin, Shafiq, Faiza, Huang, Eugene Y., Gallo, Richard L.
Format Journal Article
LanguageEnglish
Published United States Elsevier Inc 01.04.2014
Elsevier Limited
Subjects
Administration, Topical
Adult
Aged
Aged, 80 and over
Aminocaproic Acid - chemistry
Antimicrobial Cationic Peptides - metabolism
Aprotinin - chemistry
Cathelicidins
Double-Blind Method
Female
Gene Expression Regulation, Enzymologic
Humans
Inflammation
Kallikreins - metabolism
Male
Middle Aged
Peptide Hydrolases - metabolism
Pilot Projects
Rosacea - drug therapy
Rosacea - enzymology
Serine Proteases - metabolism
Serine Proteinase Inhibitors - administration & dosage
Serine Proteinase Inhibitors - therapeutic use
Skin - enzymology
Treatment Outcome
Trypsin - chemistry
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Bibliography:SourceType-Other Sources-1
ObjectType-Article-1
content type line 63
ObjectType-Correspondence-2
ObjectType-Undefined-3
ISSN:0022-202X
1523-1747
DOI:10.1038/jid.2013.472