Electrochemical sensor and biosensor platforms based on advanced nanomaterials for biological and biomedical applications

• Published in: Biosensors & bioelectronics Vol. 103; pp. 113 - 129
• Main Authors: Maduraiveeran, Govindhan, Sasidharan, Manickam, Ganesan, Vellaichamy
• Format: Journal Article
• Language: English
• Published: England Elsevier B.V 30.04.2018
• Subjects: Biology; Biomedicine; Biomolecules; Biosensing Techniques - trends; Biosensor; Biotechnology; Electrochemical analysis; Electrochemical Techniques - trends; Humans; in vivo and in vitro analysis; Nanomaterials; Nanostructures - chemistry; Sensitivity and Specificity; Biotechnology; Electrochemical analysis; Biomedicine; Biosensor; Nanomaterials; Biomolecules; Biology; in vivo and in vitro analysis
• ISSN: 0956-5663; 1873-4235
• DOI: 10.1016/j.bios.2017.12.031

Introduction of novel functional nanomaterials and analytical technologies signify a foremost possibility for the advance of electrochemical sensor and biosensor platforms/devices for a broad series of applications including biological, biomedical, biotechnological, clinical and medical diagnostics, environmental and health monitoring, and food industries. The design of sensitive and selective electrochemical biological sensor platforms are accomplished conceivably by offering new surface modifications, microfabrication techniques, and diverse nanomaterials with unique properties for in vivo and in vitro medical analysis via relating a sensibly planned electrode/solution interface. The advantageous attributes such as low-cost, miniaturization, energy efficient, easy fabrication, online monitoring, and the simultaneous sensing capability are the driving force towards continued growth of electrochemical biosensing platforms, which have fascinated the interdisciplinary research arenas spanning chemistry, material science, biological science, and medical industries. The electrochemical biosensor platforms have potential applications in the early-stage detection and diagnosis of disease as stout and tunable diagnostic and therapeutic systems. The key aim of this review is to emphasize the newest development in the design of sensing and biosensing platforms based on functional nanomaterials for biological and biomedical applications. High sensitivity and selectivity, fast response, and excellent durability in biological media are all critical aspects which will also be wisely addressed. Potential applications of electrochemical sensor and biosensor platforms based on advanced functional nanomaterials for neuroscience diagnostics, clinical, point-of-care diagnostics and medical industries are also concisely presented. •Nanomaterials based electrochemical sensor and biosensor platforms.•Novel nanomaterials used for in vivo and in vitro biomedical analysis.•Electrochemical biosensors employed for early-stage detection and diagnosis of disease.•Huge potential for neuroscience diagnostics, clinical, and medical industries.