"Après Mois, Le Déluge": Preparing for the Coming Data Flood in the MRI-Guided Radiotherapy Era

Magnetic resonance imaging provides a sea of quantitative and semi-quantitative data. While radiation oncologists already navigate a pool of clinical (semantic) and imaging data, the tide will swell with the advent of hybrid MRI/linear accelerator devices and increasing interest in MRI-guided radiot...

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Bibliographic Details
Published inFrontiers in oncology Vol. 9; p. 983
Main Authors Kiser, Kendall J, Smith, Benjamin D, Wang, Jihong, Fuller, Clifton D
Format Journal Article
LanguageEnglish
Published Switzerland Frontiers Media S.A 30.09.2019
Subjects
biomedical informatics
clinical informatics
informatics
MR LINAC
MRI
MRI-guided radiotherapy
Oncology
MRI-guided radiotherapy
biomedical informatics
radiomics
clinical informatics
MRI
informatics
MR LINAC
imaging informatics
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Summary:Magnetic resonance imaging provides a sea of quantitative and semi-quantitative data. While radiation oncologists already navigate a pool of clinical (semantic) and imaging data, the tide will swell with the advent of hybrid MRI/linear accelerator devices and increasing interest in MRI-guided radiotherapy (MRIgRT), including adaptive MRIgRT. The variety of MR sequences (of greater complexity than the single parameter Hounsfield unit of CT scanning routinely used in radiotherapy), the workflow of adaptive fractionation, and the sheer quantity of daily images acquired are challenges for scaling this technology. Biomedical informatics, which is the science of information in biomedicine, can provide helpful insights for this looming transition. Funneling MRIgRT data into clinically meaningful information streams requires committing to the flow of inter-institutional data accessibility and interoperability initiatives, standardizing MRIgRT dosimetry methods, streamlining MR linear accelerator workflow, and standardizing MRI acquisition and post-processing. This review will attempt to conceptually ford these topics using clinical informatics approaches as a theoretical bridge.
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This article was submitted to Radiation Oncology, a section of the journal Frontiers in Oncology
Reviewed by: Sunyoung Jang, Princeton Radiation Oncology Center, United States; John E. Mignano, Tufts University School of Medicine, United States
Edited by: Jing Cai, Hong Kong Polytechnic University, Hong Kong
ISSN:2234-943X
2234-943X
DOI:10.3389/fonc.2019.00983