DBS for Obesity

Obesity is a chronic, progressive and prevalent disorder. Morbid obesity, in particular, is associated with numerous comorbidities and early mortality. In patients with morbid obesity, pharmacological and behavioral approaches often have limited results. Bariatric surgery is quite effective but is a...

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Published inBrain sciences Vol. 6; no. 3; p. 21
Main Authors Franco, Ruth, Fonoff, Erich T, Alvarenga, Pedro, Lopes, Antonio Carlos, Miguel, Euripides C, Teixeira, Manoel J, Damiani, Durval, Hamani, Clement
Format Journal Article
LanguageEnglish
Published Switzerland MDPI 18.07.2016
MDPI AG
Subjects
deep brain stimulation
hypothalamus
nucleus accumbens
obesity
Review
nucleus accumbens
deep brain stimulation
hypothalamus
obesity
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Summary:Obesity is a chronic, progressive and prevalent disorder. Morbid obesity, in particular, is associated with numerous comorbidities and early mortality. In patients with morbid obesity, pharmacological and behavioral approaches often have limited results. Bariatric surgery is quite effective but is associated with operative failures and a non-negligible incidence of side effects. In the last decades, deep brain stimulation (DBS) has been investigated as a neurosurgical modality to treat various neuropsychiatric disorders. In this article we review the rationale for selecting different brain targets, surgical results and future perspectives for the use of DBS in medically refractory obesity.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
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ObjectType-Review-1
ISSN:2076-3425
2076-3425
DOI:10.3390/brainsci6030021