Potential of Curcumin-mediated Photodynamic Inactivation to reduce oral colonization

Highlights • A water-soluble mixture of curcuminoids (CRM) was proposed as photosensitizer. • CRM-mediated PDI significantly reduced the amount of pathogens in human saliva. • PDI showed similar results to 1-minute CLX

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Bibliographic Details
Published inPhotodiagnosis and photodynamic therapy Vol. 15; pp. 46 - 52
Main Authors Santezi, Carolina, Tanomaru, Juliane M, Bagnato, Vanderlei S, Júnior, Osmir B.O, Dovigo, Lívia N
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier B.V 01.09.2016
Subjects
Bacterial Load - drug effects
Bacterial Load - physiology
Bacterial Load - radiation effects
Bacterial Physiological Phenomena - drug effects
Bacterial Physiological Phenomena - radiation effects
Biological contamination
Curcumin
Curcumin - administration & dosage
Dental Disinfectants - administration & dosage
Dose-Response Relationship, Drug
Dose-Response Relationship, Radiation
Feasibility Studies
Hematology, Oncology and Palliative Medicine
Humans
Internal Medicine
Light
Photochemotherapy
Photochemotherapy - methods
Photosensitizing Agents - administration & dosage
Saliva - drug effects
Saliva - microbiology
Saliva - radiation effects
Sterilization - methods
Photochemotherapy
Curcumin
Biological Contamination
Biological contamination
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Summary:Highlights • A water-soluble mixture of curcuminoids (CRM) was proposed as photosensitizer. • CRM-mediated PDI significantly reduced the amount of pathogens in human saliva. • PDI showed similar results to 1-minute CLX
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:1572-1000
1873-1597
DOI:10.1016/j.pdpdt.2016.04.006