Coping strategies mediate the relationship between fear of cancer recurrence and quality of life in postoperative patients with prostate cancer: a multicentre survey

• Published in: BMC urology Vol. 24; no. 1; p. 49
• Main Authors: Yu, Chen, Jingzhen, Zhu, Luqiang, Zhou, Xiaojuan, Yuan, Ji, Zheng
• Format: Journal Article
• Language: English
• Published: England BioMed Central Ltd 01.03.2024; BioMed Central; BMC
• Subjects: Cancer; Cancer patients; Coping; Coping Skills; Fear; Fear of cancer recurrence; Humans; Likert scale; Lung cancer; Male; Mediation; Medical personnel; Mental health; Mortality; Patients; Prostate cancer; Prostatic Neoplasms - surgery; Public health; Quality of Life; Questionnaires; Relapse; Surgery; Surveys; Surveys and Questionnaires; Urinary incontinence; World health; Coping; Fear of cancer recurrence; Prostate cancer; Quality of life
• ISSN: 1471-2490; 1471-2490
• DOI: 10.1186/s12894-024-01428-5

The aim of the present study was to investigate the relationships between fear of cancer recurrence and quality of life in patients with prostate cancer. A model based on Lazarus' and Folkman's theory tested the specific hypothesis: fear of cancer recurrence has a direct and indirect effect on quality of life mediated by coping strategies. A questionnaire survey was conducted on 305 patients with prostate cancer who underwent radical surgery, including demographic information, FoP-Q-SF (Fear of Progression Questionnaire), MCMQ (The Medical Coping Modes Questionnaire), QLQ-C30 (Questionnaire for Quality of Life Assessment in patients with cancer, version 3.0), and a mediator model was tested using the PROCESS macro for SPSS. The total FoP-Q-SF score of 305 postoperative prostate cancer patients was 34.3 ± 5.856, with approximately 41.6% of the patients scoring higher than 34. There were significant indirect effects of fear of cancer recurrence on global health status through face [a1b1; 0.0394, Boot CIs 0.0025, 0.0819] and yield [a3b3; -0.1075, Boots CIs - 0.1657, -0.0557] but not for evasive [a2b2; 0.0235; Boots CIs - 0.057, 0.0508]. Coping strategies are the most important mediating factors between fear of cancer recurrence and QOL among patients with prostate cancer. Our results support the proposed conceptual model, based on Lazarus' and Folkman's theory. Medical personnel need to develop corresponding intervention measures based on the different coping methods of patients, promote disease recovery, and improve postoperative quality of life.