Right upper lobe intrapulmonary mature cystic teratoma. An unusual location with unusual associations and a review of the literature

• Published in: International journal of surgery case reports Vol. 90; p. 106683
• Main Authors: Awad, Ahmed K., Fatima, Aiman, Khurana, Shriya, Elbadawy, Merihan A., Elseidy, Sheref A.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.01.2022; Elsevier
• Subjects: Case Report; Computerized tomography; Intrapulmonary teratoma; Mature teratoma; Thoracic surgery; Thoracic surgery; Mature teratoma; Intrapulmonary teratoma; Computerized tomography
• ISSN: 2210-2612; 2210-2612
• DOI: 10.1016/j.ijscr.2021.106683

Teratomas are rare neoplasms made up of mature embryonic germ cell layers. Extra-gonadal teratomas are rare and primarily in the mediastinum. Mature cystic teratomas (MCT) are slow-growing benign tumors accounting for a small number of mediastinal germ cell tumors. Patients with MCT are often asymptomatic, and even most symptomatic intrapulmonary teratomas present with vague and non-specific symptoms such as cough, hemoptysis, and chest pain. A Yemeni patient presented for two years with dry cough, shortness of breath, and stitching right-sided chest pain. Plain X-ray showed pleural thickening associated with two opacities in the right lung- one located centrally in the upper lobe and another peripherally- which were confirmed with a CT scan. During right-sided decortication with resection of the two masses, extensive adhesions were found between the right pleura and the chest wall. The adhesions were released, and right-sided decortication led to the removal of the peripheral cystic mass attached to the pleura. Histopathology reported the presence of squamous epithelium lining with ectodermal components such as hair follicles, sebaceous glands, keratin debris, fatty, and fibromuscular tissue. Intrapulmonary teratomas are rare tumors, with less than 100 cases reported in the past few years. All the reported cases are in the left lung lobes, yet our case is on the right side. Although the right-sided mature cystic teratoma is even scarcer, physicians should have a high index of suspicion for teratoma when encountering abnormal lesion in the right side of the lung confirming it either by CT or MRI. •Teratomas are rare neoplasms made up of two or more mature embryonic germ cell layers•Mature cystic teratomas (MCT) are benign, slow-growing tumors and account for a small number of mediastinal germ cell tumors.•Most symptomatic intrapulmonary teratomas present with vague and non-specific symptoms such as cough, hemoptysis, and chest pain.•Mediastinal mature teratomas are often well-defined on CT showing internal heterogeneous appearances.