Rheological behavior of alginate solutions for biomanufacturing

• Published in: Journal of applied polymer science Vol. 113; no. 6; pp. 3866 - 3871
• Main Authors: Rezende, Rodrigo Alvarenga, Bártolo, Paulo Jorge, Mendes, Ausenda, Filho, Rubens Maciel
• Format: Journal Article
• Language: English
• Published: Hoboken Wiley Subscription Services, Inc., A Wiley Company 15.09.2009; Wiley
• Subjects: Alginates; Applied sciences; Biological and medical sciences; biomaterials; biopolymers; Design engineering; Exact sciences and technology; hydrogels; Loss modulus; Mathematical models; Medical sciences; Natural polymers; Optimization; Organic polymers; Physicochemistry of polymers; Properties and characterization; Reproduction; Rheological properties; rheology; Shear rate; Solution and gel properties; Starch and polysaccharides; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Technology. Biomaterials. Equipments; viscoelastic properties; Viscoelasticity; rheology; Tissue engineering; Uronide polymer; hydrogels; Alginates; Experimental study; viscoelastic properties; Polyelectrolyte; Shear viscosity; Concentration effect; Dilute solution; Oside polymer; Biomaterial; Hydrogel; Aqueous solution; biomaterials; biopolymers; Rheological properties
• ISSN: 0021-8995; 1097-4628; 1097-4628
• DOI: 10.1002/app.30170

The rheological behavior of alginate solutions were investigated for the optimal design of a biomanufacturing system to produce alginate structures for tissue engineering. Its rheological properties were determined by a rheometer through rotational and oscillatory tests. Experimental results were used to model the alginate solutions characteristics. The findings suggest that alginate solutions undergo shear-thinning effects with increasing shear rates. It is also possible to observe that its loss modulus is higher than the storage modulus ones being both modulus dependent upon the frequency, which is a typical characteristic of dilute solutions.