Impact of Freeze-Drying on Cord Blood (CB), Serum (S), and Platelet-Rich Plasma (CB-PRP) Preparations on Growth Factor Content and In Vitro Cell Wound Healing

• Published in: International journal of molecular sciences Vol. 23; no. 18; p. 10701
• Main Authors: Valente, Sabrina, Ciavarella, Carmen, Astolfi, Gloria, Bergantin, Elisa, Curti, Nico, Buzzi, Marina, Fontana, Luigi, Versura, Piera
• Format: Journal Article
• Language: English
• Published: Basel MDPI AG 14.09.2022; MDPI
• Subjects: Biological properties; Blood; Blood platelets; brain-derived growth factor; Brain-derived neurotrophic factor; Cell activation; Cell adhesion & migration; Cell cycle; Cell growth; Cord blood; Cornea; Enzyme-linked immunosorbent assay; epidermal growth factor; Eye disorders; Freeze drying; Gene expression; Glial cells; Glial fibrillary acidic protein; Growth factors; Morphology; Ophthalmology; Plasma; platelet-rich plasma; serum; Vimentin; Wound healing

Blood-based preparations are used in clinical practice for the treatment of several eye disorders. The aim of this study is to analyze the effect of freeze-drying blood-based preparations on the levels of growth factors and wound healing behaviors in an in vitro model. Platelet-rich plasma (PRP) and...