Antibacterial activity of medicinal plants on the management of mastitis in dairy cows: A systematic review

• Published in: Veterinary medicine and science Vol. 9; no. 6; pp. 2800 - 2819
• Main Authors: Kaseke, Tinotenda Blessing, Chikwambi, Zedias, Gomo, Calvin, Mashingaidze, Arnold Bray, Murungweni, Chrispen
• Format: Journal Article
• Language: English
• Published: Nottingham John Wiley & Sons, Inc 01.11.2023; Wiley
• Subjects: Animal models; antibacterial; Antibacterial activity; Antibiotic resistance; Antibiotics; antimicrobial; Antimicrobial agents; Chromatography; Clinical trials; COVID-19; Dairy cattle; Dairy industry; Dairy products; Disease transmission; Drug resistance; E coli; Economic importance; Essential oils; Ethnobotany; ethnomedicine; Flowers & plants; Food safety; Herbal medicine; Infections; Livestock; Mastitis; Medicinal plants; Medicine; Milk; Names; Oils & fats; phytochemical; Phytochemicals; Plant extracts; Public health
• ISSN: 2053-1095; 2053-1095
• DOI: 10.1002/vms3.1268

Abstract Background Mastitis is a disease of economic importance in dairy production systems. The common management regime for mastitis is the use of synthetic antibiotics, giving a new problem of antibiotic resistance. There is, therefore, a need to prospect for alternatives to conventional antibiotics from herbal plants. Objectives This systematic review evaluates the use of plants as alternatives for the control of mastitis in dairy cattle, focussing on the effectiveness of studied plants and plant‐based products and possible implications on the use of these products in livestock health. Methodology The PRISMA model was implemented with searches done in five electronic databases: Scopus, ScienceDirect, PubMed, Ovid and Research4Life. Data were extracted from 45 studies with 112 plant species from plant species belonging to 42 different families. The specific keywords were 'mastitis', 'dairy cows' and 'medicinal plants'. Results The most cited plant species included Allium sativum L., Azadirachta indica and Eucalyptus globulus Labill with the latter further exploring its components. Microbial species causing mastitis mainly were Staphylococcus aureus and Escherichia coli . The extraction methods used included maceration approach using ethanol, methanol and water as solvents for phytochemicals and chromatographic techniques for essential oils. A few studies explored the mode of action, and toxicities of the herbal extracts as well as evaluating their efficacy in clinical trials using animal models. Conclusion Plants with defined levels of phytochemicals were essential sources of antibacterials. Standardisation of analytical methods is required.