Cerebral Infarction in Duchenne Muscular Dystrophy

• Published in: Journal of stroke and cerebrovascular diseases Vol. 20; no. 3; pp. 264 - 265
• Main Authors: Tsakadze, Nina, MD, PhD, Katzin, Lara W., MD, Krishnan, Sendhil, MD, Behrouz, Réza, DO
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.05.2011
• Subjects: Adolescent; Adrenergic beta-Antagonists - therapeutic use; Angiotensin-Converting Enzyme Inhibitors - therapeutic use; Anticoagulants - therapeutic use; Cardiomyopathies - diagnosis; Cardiomyopathies - drug therapy; Cardiomyopathies - etiology; Cardiovascular; cerebral infarction; Cerebral Infarction - diagnosis; Cerebral Infarction - drug therapy; Cerebral Infarction - etiology; Diffusion Magnetic Resonance Imaging; Duchenne muscular dystrophy; Humans; Magnetic Resonance Angiography; Male; Muscular Dystrophy, Duchenne - complications; Neurology; Pons - blood supply; Stroke; stroke in the young; Treatment Outcome; Warfarin - therapeutic use; Stroke; cerebral infarction; Duchenne muscular dystrophy; stroke in the young
• ISSN: 1052-3057; 1532-8511
• DOI: 10.1016/j.jstrokecerebrovasdis.2009.12.006

Duchenne muscular dystrophy (DMD) is an X-linked form of muscular dystrophy characterized by progressive limb-girdle distribution of muscle weakness. Morbidity related to cardiomyopathy (CMO) is common, but cerebral infarction (CI) is relatively rare in these patients. We report a case of a pontine infarct in a patient with DMD and advanced CMO, and review the published data on CMO and CI in patients with DMD.