The Emotion-Regulation Benefits of Implicit Reappraisal in Clinical Depression: Behavioral and Electrophysiological Evidence

• Published in: Neuroscience bulletin Vol. 39; no. 6; pp. 973 - 983
• Main Authors: Yuan, Jiajin, Zhang, Yueyao, Zhao, Yanli, Gao, Kexiang, Tan, Shuping, Zhang, Dandan
• Format: Journal Article
• Language: English
• Published: Singapore Springer Nature Singapore 01.06.2023; Springer
• Subjects: Anatomy; Anesthesiology; Biomedical and Life Sciences; Biomedicine; Cognition - physiology; Comparative analysis; Depression; Depression, Mental; Depressive Disorder, Major - psychology; Emotional Regulation; Emotions - physiology; Human Physiology; Humans; Neurology; Neurosciences; Original Article; Pain Medicine; Depression; Late positive potential; Reappraisal; Implicit emotion regulation
• ISSN: 1673-7067; 1995-8218
• DOI: 10.1007/s12264-022-00973-z

Major depressive disorder (MDD) is characterized by emotion dysregulation. Whether implicit emotion regulation can compensate for this deficit remains unknown. In this study, we recruited 159 subjects who were healthy controls, had subclinical depression, or had MDD, and examined them under baseline, implicit, and explicit reappraisal conditions. Explicit reappraisal led to the most negative feelings and the largest parietal late positive potential (parietal LPP, an index of emotion intensity) in the MDD group compared to the other two groups; the group difference was absent under the other two conditions. MDD patients showed larger regulatory effects in the LPP during implicit than explicit reappraisal, whereas healthy controls showed a reversed pattern. Furthermore, the frontal P3, an index of voluntary cognitive control, showed larger amplitudes in explicit reappraisal compared to baseline in the healthy and subclinical groups, but not in the MDD group, while implicit reappraisal did not increase P3 across groups. These findings suggest that implicit reappraisal is beneficial for clinical depression.