Predictive value of serum albumin and calcium levels in burn patients with Pseudomonas aeruginosa infection: A comprehensive analysis of clinical outcomes

• Published in: International wound journal Vol. 21; no. 3; pp. e14786 - n/a
• Main Authors: Haghighi Bardineh, Seyed Ashkan, Balou, Heydar Ali, Sedigh Ebrahim‐Saraie, Hadi, Mobayen, Mohammadreza, Esmailzadeh, Mojdeh, Haghighi, Samane, Haghighi, Arezoo, Sadeghi, Mahsa
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.03.2024; John Wiley & Sons, Inc
• Subjects: Adult; Age; albumin; burn; Burn treatment; Burns - therapy; Calcium; Clinical outcomes; Fatalities; Homeostasis; Hospitalization; Humans; infection; Injuries; Length of stay; Medical prognosis; Mortality; Nosocomial infections; Original; Patients; Proteins; Pseudomonas Infections - diagnosis; Regression analysis; Sepsis; Serum Albumin; Statistical analysis; Trauma; Variables; Vitamin D; Iran; burn; infection; calcium; vitamin D; albumin
• ISSN: 1742-4801; 1742-481X; 1742-481X
• DOI: 10.1111/iwj.14786

In the ongoing challenge to reduce burn‐associated mortality rates, this study explores the predictive capacity of clinical factors in burn patients, focusing on vitamin D, calcium, and serum albumin levels during hospitalisation in cases with Pseudomonas aeruginosa infection. Our research involves a comprehensive analysis of 100 burn patients, encompassing crucial clinical parameters such as the burn severity index, serum albumin, vitamin D, and calcium levels at admission. Data were meticulously entered into IBM Statistics SPSS software version 28 and subjected to statistical analysis. The study reveals an average patient age of 39.75 years and a notable 34% mortality rate. Additionally, the average lengths of hospital and intensive care unit (ICU) stays are determined to be 11.33 and 7.79 days, respectively. Significantly, a correlation between calcium and albumin variables and treatment outcomes is established, showcasing their potential to predict variable changes in patient mortality rates. Furthermore, a noteworthy association is observed between serum calcium levels and the duration of ICU hospitalisation. In conclusion, albumin and calcium variables emerge as sensitive and specific indicators for predicting outcomes in burn patients. Importantly, the independence of these factors from the physician's experience and diagnosis reduces human error and thus increases the accuracy of mortality prediction in this patient population.