Uterine Leiomyosarcoma Manifesting as a Tricuspid Valve Mass

Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patien...

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Bibliographic Details
Published inCase reports in oncology Vol. 6; no. 1; pp. 119 - 126
Main Authors Marak, Creticus P., Ponea, Ana M., Alappan, Narendrakumar, Shaheen, Shagufta, Guddati, Achuta K.
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 28.02.2013
Karger Publishers
Subjects
Leiomyosarcoma
Metastasis
Published: February 2013
Pulmonary embolism
Tricuspid valve
Pulmonary embolism
Metastasis
Tricuspid valve
Leiomyosarcoma
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Summary:Uterine leiomyosarcoma is a rare malignancy and carries a poorer prognosis when compared to endometrial carcinoma. It has been observed to metastasize to all the major organs. It presents with symptoms of abdominal distension, vaginal bleeding and may pass unnoticed until an advanced stage in patients with leiomyomas. Surgery is a viable option in patients with disease limited to the uterus, but metastasis to the heart may require surgery to prevent acute and catastrophic complications. The case described here involves metastasis to the tricuspid valve, which caused severe tricuspid regurgitation in the setting of acute pulmonary embolism. Surgical resection restored cardiac function and stabilized the patient. This case illustrates a rare site of metastasis of leiomyosarcoma which required immediate intervention and resulted in a favorable outcome.
ISSN:1662-6575
1662-6575
DOI:10.1159/000346935