Malignant Triton Tumor of the Sciatic Nerve as a Secondary Malignancy after Extended Field Radiotherapy and Chemotherapy of Hodgkin's Disease

Late effects of therapy for Hodgkin's disease include secondary malignancies like leukemia, lymphoma or solid tumors developing after long periods of latency. Ionizing radiation often causes the last group. The highest risks have been described for induced breast and lung cancers. We are the fi...

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Bibliographic Details
Published inCase reports in oncology Vol. 7; no. 1; pp. 239 - 245
Main Authors Nitsche, Mirko, Reible, Michael, Pflüger, Karl-Heinz, Bergmann, Markus, Hermann, Robert Michael
Format Journal Article
LanguageEnglish
Published Basel, Switzerland S. Karger AG 28.03.2014
Karger Publishers
Subjects
Hodgkin’s disease
Published: March 2014
Radiotherapy
Second malignancy
Triton tumor
Hodgkin’s disease
Radiotherapy
Second malignancy
Triton tumor
Hodgkin's disease
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Summary:Late effects of therapy for Hodgkin's disease include secondary malignancies like leukemia, lymphoma or solid tumors developing after long periods of latency. Ionizing radiation often causes the last group. The highest risks have been described for induced breast and lung cancers. We are the first to report a malignant triton tumor (MTT) as a secondary malignancy after radiotherapy and chemotherapy for Hodgkin's lymphoma. MTT is a very rare subtype of malignant peripheral nerve sheath tumors with rhabdomyoblastic differentiation and an aggressive course of disease.
ISSN:1662-6575
1662-6575
DOI:10.1159/000360576