Exploring rapid chemical separations of Sc-47 produced from photonuclear reactions on natural vanadium targets

• Published in: Journal of radioanalytical and nuclear chemistry Vol. 331; no. 12; pp. 5623 - 5630
• Main Authors: Meiers, Jessica L., Foley, Ari, Beattie, Caitlin, Snow, Mathew S.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 01.12.2022; Springer; Springer Nature B.V
• Subjects: 07 ISOTOPE AND RADIATION SOURCES; Bremsstrahlung; Chelation; Chemical separation; Chemistry; Chemistry and Materials Science; Diagnostic Radiology; Hadrons; Heavy Ions; Hydrogen peroxide; Inorganic Chemistry; Irradiation; Nuclear Chemistry; Nuclear Physics; photonuclear; Photonuclear reactions; Physical Chemistry; Purity; RADIATION CHEMISTRY, RADIOCHEMISTRY, AND NUCLEAR CHEMISTRY; rapid chemistry; Sc-47; Scandium; Scandium-47; SPECT; SPECT imaging; Vanadium; Rapid chemistry; Scandium-47; SPECT; Photonuclear; Sc-47
• ISSN: 0236-5731; 1588-2780
• DOI: 10.1007/s10967-022-08611-8

Scandium-47 ( 47 Sc) production via bremsstrahlung irradiation of natural vanadium targets offers significant advantages for producing high purity 47 Sc; this work evaluates several rapid dissolution and chemical separation techniques for recovering high purity 47 Sc from irradiated vanadium. Techniques developed are combined into a simple, gram-scale, semi-automated target processing system that enables 47 Sc recovery from irradiated vanadium targets with chemical yields as high as 93 ± 3% and 47 Sc/V separation factors of 6 ± 3 ·10 11 within 90 min total processing times. Future research into H 2 O 2 resistant separation techniques and their applicability for direct process coupling to chelation are recommended.