Structure of a novel 22-homo-23-norcholestane trisaccharide from Ornithogalum saundersiae

A novel 22-homo-23-norcholestane trisaccharide, which showed an unique inhibitory pattern on cyclic AMP phosphodiesterase, was isolated from the bulbs of Ornithogalum saundersiae. The structure was determined by extensive 2D NMR analysis and hydrolysis. The structure of 1 was determined by extensive...

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Bibliographic Details
Published inTetrahedron letters Vol. 34; no. 38; pp. 6073 - 6076
Main Authors Kuroda, Minpei, Mimaki, Yoshihiro, Sashida, Yutaka, Nikaido, Tamotsu, Ohmoto, Taichi
Format Journal Article
LanguageEnglish
Published Oxford Elsevier Ltd 17.09.1993
Elsevier
Subjects
Analytical, structural and metabolic biochemistry
Biological and medical sciences
bulbs
cholestanes
cyclic amp phosphodiesterase
enzyme inhibitors
Fundamental and applied biological sciences. Psychology
Ornithogalum
Other biological molecules
phosphoric diester hydrolases
structure
Terpenes, steroids. Hormones
trisaccharides
Steroid
Monocotyledones
Aldose
Molecular structure
Enzyme
Overhauser effect
Enzyme inhibitor
Polycyclic compound
Esterases
Hemiacetal
Phosphoric diester hydrolases
Oxygen heterocycle
Biological activity
Two dimension spectrometry
Acetal
Liliaceae
Angiospermae
Hydrolases
Isolation
Spermatophyta
Glycoside
NMR spectrum
Trisaccharide
Pulse sequence
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Summary:A novel 22-homo-23-norcholestane trisaccharide, which showed an unique inhibitory pattern on cyclic AMP phosphodiesterase, was isolated from the bulbs of Ornithogalum saundersiae. The structure was determined by extensive 2D NMR analysis and hydrolysis. The structure of 1 was determined by extensive 2D NMR analysis and hydrolysis.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0040-4039
1873-3581
DOI:10.1016/S0040-4039(00)61731-8