Acute leukemia with megakaryocytic predominance

A case of acute leukemia with very marked megakaryocytic predominance is reported. Cytologic, cytochemical, electron microscopic, and platelet function studies are described. The most striking finding is abnormal accumulation of glycogen in the platelets and in megakaryocytes and their precursors. T...

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Bibliographic Details
Published inCancer Vol. 28; no. 5; pp. 1343 - 1349
Main Authors Chan, B. W. B., Flemans, R. J., Zbinden, G.
Format Journal Article
LanguageEnglish
Published New York Wiley Subscription Services, Inc., A Wiley Company 1971
Subjects
Acute Disease
Adult
Autopsy
Blood Platelets - analysis
Bone Marrow - analysis
Bone Marrow Cells
Female
Glycogen - analysis
Histocytochemistry
Humans
Leukemia - complications
Leukemia - metabolism
Leukemia - pathology
Leukemia - physiopathology
Megakaryocytes - analysis
Microscopy, Electron
Platelet Adhesiveness
Staining and Labeling
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Summary:A case of acute leukemia with very marked megakaryocytic predominance is reported. Cytologic, cytochemical, electron microscopic, and platelet function studies are described. The most striking finding is abnormal accumulation of glycogen in the platelets and in megakaryocytes and their precursors. The relationship to other forms of acute leukemia is discussed.
Bibliography:Chief Technician.
Research Associate.
Senior Medical Registrar. Holder of an Elmore Research Studentship of the University of Cambridge.
ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0008-543X
1097-0142
DOI:10.1002/1097-0142(1971)28:5<1343::AID-CNCR2820280538>3.0.CO;2-1