Correction of Cerebrospinal Fluid Protein in Infants With Traumatic Lumbar Punctures

In our multicenter cohort of infants ≤60 days of age, we identified 2646 infants with a traumatic lumbar puncture, of which 31 (1.2%) had bacterial meningitis. For every 1000 cerebrospinal fluid red blood cells/mm, cerebrospinal (cerebrospinal fluid) protein increased 1.1 mg/dL (95% confidence inter...

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Bibliographic Details
Published inThe Pediatric infectious disease journal Vol. 36; no. 10; p. 1006
Main Authors Lyons, Todd W, Cruz, Andrea T, Freedman, Stephen B, Arms, Joseph L, Aronson, Paul L, Fleming, Alesia H, Kulik, Dina M, Mahajan, Prashant, Mistry, Rakesh D, Pruitt, Christopher M, Thompson, Amy D, Nigrovic, Lise E
Format Journal Article
LanguageEnglish
Published United States 01.10.2017
Subjects
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - therapeutic use
Area Under Curve
Blood Proteins - cerebrospinal fluid
Cerebrospinal Fluid Proteins - cerebrospinal fluid
Erythrocytes - chemistry
Female
Humans
Infant
Infant, Newborn
Male
Meningitis, Bacterial - cerebrospinal fluid
Meningitis, Bacterial - diagnosis
Meningitis, Bacterial - drug therapy
Spinal Puncture - adverse effects
Time-to-Treatment
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Summary:In our multicenter cohort of infants ≤60 days of age, we identified 2646 infants with a traumatic lumbar puncture, of which 31 (1.2%) had bacterial meningitis. For every 1000 cerebrospinal fluid red blood cells/mm, cerebrospinal (cerebrospinal fluid) protein increased 1.1 mg/dL (95% confidence interval: 1.0-1.2 mg/dL).
ISSN:1532-0987
DOI:10.1097/INF.0000000000001634