Serological Detection of a Cell-Surface Antigen Specified by the T (Brachyury) Mutant Gene in the House Mouse

A cell-surface component specified by a mutant gene at the T-locus in the mouse has been detected on sperm by serological methods. The gene product thus recognized is not present on other adult cells.

Saved in:
Bibliographic Details
Published inProceedings of the National Academy of Sciences - PNAS Vol. 69; no. 8; pp. 2076 - 2080
Main Authors Bennett, Dorothea, Goldberg, Ellen, Dunn, L. C., Boyse, Edward A.
Format Journal Article
LanguageEnglish
Published United States National Academy of Sciences of the United States of America 01.08.1972
National Acad Sciences
Subjects
Alleles
Animals
Antibody Specificity
Antigen-Antibody Reactions
Antigens
Antigens - analysis
Antiserum
Biological Sciences: Genetics
Brain - immunology
Cell Membrane - immunology
Cellular differentiation
Cytotoxicity
Cytotoxicity Tests, Immunologic
Epidermal cells
Genes, Lethal
Haploidy
Heterozygotes
Lymphocytes
Lymphocytes - immunology
Male
Mice
Mice, Inbred Strains
Mutation
Spermatozoa
Spermatozoa - immunology
Tail - abnormalities
Testis - immunology
Thymus Gland - immunology
Online AccessGet full text

Cover

More Information
Summary:A cell-surface component specified by a mutant gene at the T-locus in the mouse has been detected on sperm by serological methods. The gene product thus recognized is not present on other adult cells.
Bibliography:Present address: Department of Microbiology, University of New Mexico Medical School, Albuquerque, N.Mex. 87106.
ISSN:0027-8424
1091-6490
DOI:10.1073/pnas.69.8.2076