Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer

Among patients with endoscopically resected early gastric cancers who were infected with Helicobacter pylori , the incidence of metachronous gastric cancer was 50% lower among those who received active treatment with antibiotics than among controls.

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Bibliographic Details
Published inThe New England journal of medicine Vol. 378; no. 12; pp. 1085 - 1095
Main Authors Choi, Il Ju, Kook, Myeong-Cherl, Kim, Young-Il, Cho, Soo-Jeong, Lee, Jong Yeul, Kim, Chan Gyoo, Park, Boram, Nam, Byung-Ho
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 22.03.2018
Subjects
Adenoma
Adenoma - surgery
Adult
Aged
Amoxicillin - therapeutic use
Anti-Bacterial Agents - therapeutic use
Antibiotics
Atrophy
Bacterial infections
Biopsy
Clarithromycin - therapeutic use
Classification
Double-Blind Method
Drug Therapy, Combination
Endoscopy
Enrollments
Eradication
Evidence-based medicine
Female
Follow-Up Studies
Gastric cancer
Gastric mucosa
Gastritis, Atrophic - etiology
Gastroscopy
Helicobacter Infections - complications
Helicobacter Infections - drug therapy
Helicobacter pylori
Humans
Incidence
Infections
Intention to Treat Analysis
Kaplan-Meier Estimate
Long-term effects
Male
Meta-analysis
Metastasis
Middle Aged
Motivation
Neoplasm Recurrence, Local - epidemiology
Neoplasm Recurrence, Local - etiology
Neoplasm Recurrence, Local - prevention & control
Patients
Prospective Studies
Proton Pump Inhibitors - therapeutic use
Rabeprazole - therapeutic use
Stomach - pathology
Stomach Neoplasms - epidemiology
Stomach Neoplasms - etiology
Stomach Neoplasms - prevention & control
Stomach Neoplasms - surgery
Systematic review
Tumors
South Korea
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More Information
Summary:Among patients with endoscopically resected early gastric cancers who were infected with Helicobacter pylori , the incidence of metachronous gastric cancer was 50% lower among those who received active treatment with antibiotics than among controls.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-News-1
ObjectType-Feature-3
content type line 23
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa1708423