Rapid vibrational imaging with sum frequency generation microscopy

We demonstrate rapid vibrational imaging based on sum frequency generation (SFG) microscopy with a collinear excitation geometry. Using the tunable picosecond pulses from a high-repetition-rate optical parametric oscillator, vibrationally selective imaging of collagen fibers is achieved with submicr...

Full description

Saved in:
Bibliographic Details
Published inOptics letters Vol. 36; no. 19; p. 3891
Main Authors Raghunathan, Varun, Han, Yang, Korth, Olaf, Ge, Nien-Hui, Potma, Eric Olaf
Format Journal Article
LanguageEnglish
Published United States 01.10.2011
Online AccessGet more information

Cover

More Information
Summary:We demonstrate rapid vibrational imaging based on sum frequency generation (SFG) microscopy with a collinear excitation geometry. Using the tunable picosecond pulses from a high-repetition-rate optical parametric oscillator, vibrationally selective imaging of collagen fibers is achieved with submicrometer lateral resolution. We furthermore show simultaneous SFG and second harmonic generation imaging to emphasize the compatibility of the microscope with other nonlinear optical modalities.
ISSN:1539-4794
DOI:10.1364/OL.36.003891