Pharmacokinetic Studies of the Fragrance Compound 1,8-Cineol in Humans during Inhalation
The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after ∼18 min. The elimination of this fragrance compound from th...
Saved in:
Published in | Chemical senses Vol. 21; no. 4; pp. 477 - 480 |
---|---|
Main Authors | , , , , , , |
Format | Journal Article Conference Proceeding |
Language | English |
Published |
Oxford
Oxford University Press
01.08.1996
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | The present study was undertaken to investigate the pharmacokinetics of 1,8-cineol in human subjects during prolonged inhalation. The results showed that 1,8-cineol is well absorbed from breathing air, with a peak plasma concentration after ∼18 min. The elimination of this fragrance compound from the blood is biphasic, with a mean distribution half-life of 6.7 min and an elimination half-life of 104.6 min. Chem. Senses 21: 477–480, 1996. |
---|---|
Bibliography: | istex:A564B2A1126A51B2E2C722E10CFB04824D13409E Correspondence to be sent to: Walter Jäger, Institute of Pharmaceutical Chemistry, University of Vienna, Althanstrasse 14, A-1090 Vienna, Austria ArticleID:21.4.477 ark:/67375/HXZ-P6Z0V3CN-R ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
ISSN: | 0379-864X 1464-3553 |
DOI: | 10.1093/chemse/21.4.477 |