Xenon enhanced CT for analysis of cerebral integrity, perfusion, and blood flow

Enhancement of the brain substance for CT evaluation using inhaled Xenon is confirmed. This technique was applied to the study of the normal and the embolized adolescent baboon. Healthy cerebral tissue enhances symmetrically, while abnormal areas show significantly diminished enhancement. At maximal...

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Bibliographic Details
Published inStroke (1970) Vol. 9; no. 2; pp. 123 - 130
Main Authors Drayer, B P, Wolfson, S K, Reinmuth, O M, Dujovny, M, Boehnke, M, Cook, E E
Format Journal Article
LanguageEnglish
Published United States 01.03.1978
Subjects
Animals
Brain - diagnostic imaging
Cerebrovascular Circulation
Haplorhini
Papio
Perfusion
Radiographic Image Enhancement - methods
Tomography, X-Ray Computed
Xenon Radioisotopes
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Summary:Enhancement of the brain substance for CT evaluation using inhaled Xenon is confirmed. This technique was applied to the study of the normal and the embolized adolescent baboon. Healthy cerebral tissue enhances symmetrically, while abnormal areas show significantly diminished enhancement. At maximal enhancement, an indication of gross comparative cerebral perfusion to obtained. By obtaining serial CT scans over a 10 minute time interval, the clearance rate of Xenon (cerebral blood flow) may be evaluated. Xenon-enhanced CT enables a visual and numerical analysis of both brain morphology and physiology.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0039-2499
1524-4628
DOI:10.1161/01.str.9.2.123