Antibiotic-Resistant Infections and Treatment Challenges in the Immunocompromised Host

This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ transplant recipients, the neutropenic host, and persons with human immunodeficiency virus and AIDS. Specific mechanisms of resistance in both gra...

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Bibliographic Details
Published inInfectious disease clinics of North America Vol. 30; no. 2; p. 465
Main Authors Dumford, 3rd, Donald M, Skalweit, Marion
Format Journal Article
LanguageEnglish
Published United States 01.06.2016
Subjects
Anti-Bacterial Agents - administration & dosage
Anti-Bacterial Agents - pharmacology
Anti-Bacterial Agents - therapeutic use
Bacteria - drug effects
Bacteria - pathogenicity
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Drug Resistance, Multiple, Bacterial
HIV Infections
Humans
Immunocompromised Host
Transplant Recipients
HIV/AIDS
Infection
MDRO
Organ transplant recipients
Immunocompromise
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Summary:This article reviews antibiotic resistance and treatment of bacterial infections in the growing number of patients who are immunocompromised: solid organ transplant recipients, the neutropenic host, and persons with human immunodeficiency virus and AIDS. Specific mechanisms of resistance in both gram-negative and gram-positive bacteria, as well as newer treatment options are addressed elsewhere, and are only briefly discussed in the context of the immunocompromised host.
ISSN:1557-9824
DOI:10.1016/j.idc.2016.02.008