The Future of Psychiatric Research: Genomes and Neural Circuits

The burden of neuropsychiatric illnesses is enormous. These conditions, which include schizophrenia, mood disorders, and autism, affect thought, emotions, and a person's very sense of self. Together, they are the leading cause of disability in North America and Europe and constitute 40% of all...

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Published inScience (American Association for the Advancement of Science) Vol. 327; no. 5973; pp. 1580 - 1581
Main Authors Akil, Huda, Brenner, Sydney, Kandel, Eric, Kendler, Kenneth S., King, Mary-Claire, Scolnick, Edward, Watson, James D., Zoghbi, Huda Y.
Format Journal Article
LanguageEnglish
Published American Association for the Advancement of Science 26.03.2010
Subjects
Animal models
Autism
Behavioral neuroscience
Circuits
Disabilities
Diseases
Disorders
Emotions
Genomes
Illnesses
Medical genetics
Mental illness
Nervous system diseases
Neural conduction
Neurons
Policy Forum
Productivity
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Summary:The burden of neuropsychiatric illnesses is enormous. These conditions, which include schizophrenia, mood disorders, and autism, affect thought, emotions, and a person's very sense of self. Together, they are the leading cause of disability in North America and Europe and constitute 40% of all years lost to disability. In the United States, the cost in lost earnings due to psychiatric disease is estimated conservatively to be $200 billion per year (1). The burden to individuals, families, and society is all the more tragic because these illnesses typically begin early in life, are life- long, and damage the affected individuals' self-perception, productivity, and ability to relate to others.
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ISSN:0036-8075
1095-9203
DOI:10.1126/science.1188654