Pregnancy outcome after early detection of bacterial vaginosis

To assess if detecting bacterial vaginosis either in early pregnancy or at midtrimester may predict adverse pregnancy outcome in women at risk for preterm delivery. 242 pregnant women with a previous preterm delivery were evaluated for bacterial vaginosis either in the first trimester (prior to 10 +...

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Published inEuropean journal of obstetrics & gynecology and reproductive biology Vol. 128; no. 1; pp. 40 - 45
Main Authors Guerra, Brunella, Ghi, Tullio, Quarta, Simona, Morselli-Labate, Antonio Maria, Lazzarotto, Tiziana, Pilu, Gianluigi, Rizzo, Nicola
Format Journal Article
LanguageEnglish
Published Shannon Elsevier Ireland Ltd 01.09.2006
Elsevier
Subjects
Abortion, Spontaneous - microbiology
Adult
Bacterial vaginosis
Biological and medical sciences
Diseases of mother, fetus and pregnancy
Female
Gynecology. Andrology. Obstetrics
Humans
Infant, Newborn
Medical sciences
Miscarriage
Odds Ratio
Pregnancy
Pregnancy Complications - microbiology
Pregnancy Outcome
Pregnancy Trimesters
Pregnancy. Fetus. Placenta
Premature Birth - etiology
Preterm delivery
Vaginal flora
Vaginosis, Bacterial - complications
Bacterial vaginosis
Vaginal flora
Miscarriage
Preterm delivery
Prognosis
Pregnancy disorders
Gynecology
Premature delivery
Vaginal diseases
Microflora
Abortion
Obstetrics
Female genital diseases
Infection
Bacteriosis
Early pregnancy
Diagnosis
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Summary:To assess if detecting bacterial vaginosis either in early pregnancy or at midtrimester may predict adverse pregnancy outcome in women at risk for preterm delivery. 242 pregnant women with a previous preterm delivery were evaluated for bacterial vaginosis either in the first trimester (prior to 10 + 0 weeks) or in the second one (24–26 weeks). Adverse outcome was intended as miscarriage (≤25 weeks), or premature delivery (≤36 + 6). The risk of adverse pregnancy outcome was significantly increased in women diagnosed at first trimester with bacterial vaginosis (OR: 4.56; 95% CI: 2.54–8.93); the same finding at midtrimester did not increase significantly the risk of preterm delivery. Early screening for bacterial vaginosis in pregnant women who experienced a preterm delivery may help in predicting the risk of adverse outcome.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:0301-2115
1872-7654
DOI:10.1016/j.ejogrb.2005.12.024