Brevibacillus laterosporus : A Probiotic with Important Applications in Crop and Animal Production

• Published in: Microorganisms (Basel) Vol. 12; no. 3; p. 564
• Main Authors: Liu, Yucheng, Zai, Xueying, Weng, Guangying, Ma, Xianyong, Deng, Dun
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 12.03.2024; MDPI
• Subjects: Agricultural production; Animal production; Antiinfectives and antibacterials; Antimicrobial peptides; Bacteria; Bactericidal activity; Biological control; Biosynthesis; Brevibacillus laterosporus; Cell membranes; Clinical medicine; crop cultivation; Crop diseases; Crop growth; Crop production; Crops; Cultivation; Efficiency; Environmental protection; Fungi; Genomes; Hormones; Intestinal microflora; Lipids; Lipopolysaccharides; Membrane permeability; Metabolites; Microorganisms; Nematodes; Nutrients; Pathogens; Peptides; Peptidoglycans; Phosphorus; Phylogenetics; Polyvinyl alcohol; probiotic mechanisms; Probiotics; Review; Brevibacillus laterosporus; antimicrobial peptides; crop cultivation; probiotic mechanisms; animal production
• ISSN: 2076-2607; 2076-2607
• DOI: 10.3390/microorganisms12030564

( ) is widely distributed in nature and demonstrates significant potential for applications in biological control, environmental protection, agricultural production, and clinical medicine. This review provides a comprehensive overview of the applications of in crop cultivation and animal feeding, as well as an examination of the antimicrobial peptides produced by and their antibacterial mechanisms. enhances crop cultivation by secreting hydrolases to improve nutrient absorption capabilities, synthesizing hormones to promote crop growth, and producing proteins to inhibit the reproduction of harmful organisms. has been used to improve animal production by regulating the structure of the intestinal microbiota and inhibiting the growth of pathogenic bacteria through the secretion of various antimicrobial peptides. The bactericidal activity of Brevilaterins secreted by is attributed to their ability to bind to lipopolysaccharide/lipid II molecules on the cell membrane, thereby altering permeability. Brevilaterins also inhibit bacterial reproduction by affecting relevant gene pathways in the cell membranes of pathogenic bacteria. These pathways include ATP synthesis, peptidoglycan biosynthesis, membrane transport, and cellular metabolism. In conclusion, exhibits substantial potential as a probiotic activity in crop and animal production. However, applications of in animal production could be improved, necessitating further research to elucidate the underlying probiotic mechanisms.